ClpC1 NTD Protein, Mycobacterium tuberculosis (His)
ClpC1 NTD Protein, the ATP-dependent specificity component of the Clp protease, directs the protease to specific substrates and exhibits chaperone functions independently of ClpP. It plays a crucial role in the targeted degradation of substrates, such as the anti-sigma-E factor RseA, in the presence of ClpP2. ClpC1 NTD Protein, Mycobacterium tuberculosis (His) is the recombinant ClpC1 NTD protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Others
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
ClpC1 NTD Protein, the ATP-dependent specificity component of the Clp protease, directs the protease to specific substrates and exhibits chaperone functions independently of ClpP. It plays a crucial role in the targeted degradation of substrates, such as the anti-sigma-E factor RseA, in the presence of ClpP2. ClpC1 NTD Protein, Mycobacterium tuberculosis (His) is the recombinant ClpC1 NTD protein, expressed by E. coli , with N-6*His labeled tag.
Background
As the ATP-dependent specificity component of the Clp protease, ClpC1 NTD protein plays a pivotal role in directing the protease to specific substrates. In addition to its role in substrate specificity, ClpC1 NTD exhibits chaperone functions even in the absence of ClpP. Notably, this protein is involved in the degradation of the anti-sigma-E factor RseA when in the presence of ClpP2, underscoring its significance in targeted protein degradation processes.
Technical Parameters
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Species Others
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Source E. coli
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Tag N-6*His
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Accession
P9WPC9 (M1-Y145)
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Gene ID45427583
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Molecular Construction
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N-term
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6*His
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ClpC1 NTD (M1-Y145)
Accession # P9WPC9 -
C-term
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Protein Length
Partial
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Synonyms
Rv3596c; MTCY07H7B.26; clpC1; ATP-dependent Clp protease ATP-binding subunit ClpC1
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AA Sequence
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGY
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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