CLP290 

Cat. No.: HY-103023
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CLP290 is an orally available activator of the neuron-specific K+-Cl cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ rats.

For research use only. We do not sell to patients.

CLP290 Chemical Structure

CLP290 Chemical Structure

CAS No. : 1181083-81-7

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Description

CLP290 is an orally available activator of the neuron-specific K+-Cl cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ rats[1][2].

IC50 & Target

KCC2[1]

Molecular Weight

404.46

Formula

C₁₉H₂₁FN₄O₃S

CAS No.

1181083-81-7

SMILES

O=C(N1CCCC1)OC2=CC(F)=CC=C2/C=C(SC(N3CCCCN3)=N4)/C4=O

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CLP290
Cat. No.:
HY-103023
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