Search Result
Results for "
DSPE-PEG3400
" in MedChemExpress (MCE) Product Catalog:
76
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-143209B
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Liposome
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Cancer
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DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency .
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- HY-W440916
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Liposome
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Others
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DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440881
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-DBCO sodium can be used in drug delivery research .
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- HY-W441009A
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Liposome
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Others
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DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
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- HY-W440833
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Liposome
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Others
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DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.
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- HY-P5112A
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Azido-PEG3-FLAG TFA
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Biochemical Assay Reagents
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Others
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Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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- HY-172279C
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Liposome
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Infection
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DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
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- HY-172699A
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Liposome
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Cancer
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DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
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- HY-W440886
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Liposome
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Others
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DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
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- HY-W440912
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Liposome
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Others
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DSPE-PEG3400-Cy5 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-P5112
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Azido-PEG3-FLAG
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Biochemical Assay Reagents
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Others
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Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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- HY-169089
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Drug Derivative
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Cancer
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RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
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- HY-W440835D
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG3400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-172470A
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Liposome
EGFR
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Cancer
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DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
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- HY-172494A
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Liposome
Integrin
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Cancer
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DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
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- HY-172273C
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Liposome
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Cancer
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DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-P11270
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BGM0504; BG128
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Insulin Receptor
GLP Receptor
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Metabolic Disease
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Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
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- HY-172278C
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Liposome
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Cancer
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DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
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- HY-172681A
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Liposome
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Inflammation/Immunology
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DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
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- HY-167028B
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-alkyne is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-alkyne can be used in drug delivery research .
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- HY-172482A
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Liposome
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Cancer
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DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
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- HY-172687A
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Liposome
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Cardiovascular Disease
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DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
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- HY-172684A
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Liposome
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Others
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DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
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- HY-172696A
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Liposome
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Inflammation/Immunology
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DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
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- HY-172726A
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Liposome
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Cancer
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DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
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- HY-172277C
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Liposome
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Neurological Disease
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DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
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- HY-172280C
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Liposome
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Cancer
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DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
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- HY-172708A
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Liposome
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Neurological Disease
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DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
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- HY-172464A
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Liposome
Integrin
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Cancer
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DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
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- HY-140734
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PROTAC Linkers
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Cancer
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DSPE-PEG3400-Amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-172702A
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Liposome
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Cancer
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DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
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- HY-172476A
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Liposome
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Cancer
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DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
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- HY-172723A
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Liposome
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Cancer
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DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
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- HY-144000D
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- HY-172503A
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Liposome
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Cancer
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DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
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- HY-179677A
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Liposome
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Others
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DSPE-PEG3400-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG3400-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
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- HY-174950B
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-Pyrene is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery .
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- HY-W440881A
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Liposome
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DSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research .
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- HY-172497A
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Liposome
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Cancer
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DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
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- HY-172705A
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Liposome
nAChR
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Infection
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DSPE-PEG3400-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG3400-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG3400-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions
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- HY-172479A
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Liposome
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Cancer
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DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
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- HY-176509B
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Liposome
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Others
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DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
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- HY-172500A
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Liposome
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Cancer
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DSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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- HY-W440892
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-OH is an amphiphilic polydisperse PEG which can spontaneously self-assemble in aqueous solution. The polymer can be used to prepare liposoome for targeted drug delivery.
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- HY-W440897
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
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- HY-W440900
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-SPDP is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs (
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- HY-172711A
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Liposome
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Cancer
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DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
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- HY-172473A
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Liposome
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Cancer
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DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
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- HY-W440888B
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
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- HY-W440920
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Liposome
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Others
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DSPE-PEG3400-Rhodamine is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-172276C
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Liposome
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Cancer
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DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
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- HY-W440884
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-Ald is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond.
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- HY-W440909
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Liposome
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Others
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DSPE-PEG3400-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440902
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-IA is an iodoacetyll PEG lipid. The polymer can form lipid bilayer or micelles spontaneoulsy in water. The lipophilic tails can be used to encapsulate hydrophobic therapeutic agents while the hydrophilic head can be used to encapuslate hydrophilic drugs/nutrient, such as antibody, mRNA/DNA. The iodoacetyl group is reactive with thiol to produce a thioether linkage.
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- HY-172283C
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Liposome
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Cancer
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DSPE-PEG3400-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172714A
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Liposome
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Infection
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DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172272C
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Liposome
VEGFR
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Cancer
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DSPE-PEG3400-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
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- HY-172271C
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Liposome
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Cancer
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DSPE-PEG3400-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 targets tumor-associated lymphatic vessels and macrophages .
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- HY-169089A
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Drug Derivative
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Cancer
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RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
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- HY-P10319
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PKA
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Cardiovascular Disease
Cancer
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RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
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- HY-D2887D
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Rhodamine B-PEG3400-DSPE
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Fluorescent Dye
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Others
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RB-PEG3400-DSPE (Rhodamine B-PEG3400-DSPE) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG3400-DSPE can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=546/610 nm) .
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- HY-W440830
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-COOH is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-COOH can be used in drug delivery research .
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- HY-182100B
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Liposome
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Others
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DSPE-PEG3400-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG3400-MTP can be used for drug delivery .
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- HY-168374C
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG3400-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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- HY-182101B
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Liposome
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Others
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DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
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- HY-W1052981D
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Biochemical Assay Reagents
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Others
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DSPE-PEG3400-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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- HY-172485A
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Liposome
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Cancer
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DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
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- HY-172275C
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Liposome
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Inflammation/Immunology
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DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
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- HY-182099B
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Liposome
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Cancer
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DSPE-PEG3400-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG3400-DHLASLWWGTEL can be used for drug delivery .
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- HY-177204B
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Liposome
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Cardiovascular Disease
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DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
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- HY-W1123942B
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- HY-182092C
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Liposome
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Others
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DSPE-PEG3400-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG3400-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
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- HY-182097A
-
|
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Liposome
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Inflammation/Immunology
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DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
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- HY-174901B
-
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Biochemical Assay Reagents
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Others
|
|
DSPE-PEG3400-Furan is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery .
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-
- HY-177205B
-
|
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Liposome
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Cardiovascular Disease
|
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DSPE-PEG3400-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG3400-CGKRK can be used for drug delivery .
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-
- HY-182094B
-
|
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Liposome
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Metabolic Disease
|
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DSPE-PEG3400-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG3400-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
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-
- HY-182095B
-
|
|
Liposome
|
Cardiovascular Disease
|
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DSPE-PEG3400-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG3400-CTP can be used for drug delivery .
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-
- HY-172488A
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Liposome
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Cancer
|
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DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
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-
- HY-172690A
-
|
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Liposome
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Cancer
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|
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
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-
- HY-182096B
-
|
|
Liposome
|
Neurological Disease
|
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DSPE-PEG3400-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG3400-KTP can be used for drug delivery .
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-
- HY-172491A
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|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
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-
- HY-182098B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG3400-GALA can be used for drug delivery .
|
-
- HY-174896B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG3400-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
|
-
- HY-W440906
-
|
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Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG3400-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
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-
- HY-172466A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
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-
- HY-172270C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-P11488
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P11485
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W440916
-
|
|
Fluorescent Dyes
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-D2887D
-
|
Rhodamine B-PEG3400-DSPE
|
Fluorescent Dyes
|
|
RB-PEG3400-DSPE (Rhodamine B-PEG3400-DSPE) is a PEG phospholipid labeled Rhodamine B (HY-Y0016). RB-PEG3400-DSPE can be used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=546/610 nm) .
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| Cat. No. |
Product Name |
Type |
-
- HY-143209B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency .
|
-
- HY-W440916
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440881
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-DBCO sodium can be used in drug delivery research .
|
-
- HY-W441009A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W440833
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.
|
-
- HY-172279C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
|
-
- HY-172699A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
|
-
- HY-W440886
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
|
-
- HY-W440912
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Cy5 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440835D
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG3400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-172470A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
-
- HY-172494A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
|
-
- HY-172273C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
|
-
- HY-172278C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-172681A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
|
-
- HY-167028B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-alkyne is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-alkyne can be used in drug delivery research .
|
-
- HY-172482A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
|
-
- HY-172687A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172684A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
-
- HY-172696A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
|
-
- HY-172726A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
|
-
- HY-172277C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
|
-
- HY-172280C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
|
-
- HY-172708A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-172464A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
|
-
- HY-172702A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
-
- HY-172476A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
|
-
- HY-172723A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
-
- HY-144000D
-
-
- HY-172503A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-179677A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG3400-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
|
-
- HY-174950B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Pyrene is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery .
|
-
- HY-172497A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
-
- HY-172705A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG3400-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG3400-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions
|
-
- HY-172479A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
|
-
- HY-176509B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
|
-
- HY-172500A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
-
- HY-W440892
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-OH is an amphiphilic polydisperse PEG which can spontaneously self-assemble in aqueous solution. The polymer can be used to prepare liposoome for targeted drug delivery.
|
-
- HY-W440897
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
|
-
- HY-W440900
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-SPDP is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs (
|
-
- HY-172711A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
|
-
- HY-172473A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
|
-
- HY-W440888B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440920
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Rhodamine is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-172276C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
|
-
- HY-W440884
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Ald is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond.
|
-
- HY-W440909
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440902
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-IA is an iodoacetyll PEG lipid. The polymer can form lipid bilayer or micelles spontaneoulsy in water. The lipophilic tails can be used to encapsulate hydrophobic therapeutic agents while the hydrophilic head can be used to encapuslate hydrophilic drugs/nutrient, such as antibody, mRNA/DNA. The iodoacetyl group is reactive with thiol to produce a thioether linkage.
|
-
- HY-172283C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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-
- HY-172714A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
- HY-172272C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
- HY-172271C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 targets tumor-associated lymphatic vessels and macrophages .
|
- HY-W440830
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-COOH is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-COOH can be used in drug delivery research .
|
- HY-182100B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG3400-MTP can be used for drug delivery .
|
- HY-168374C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG3400-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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- HY-182101B
-
|
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Biochemical Assay Reagents
|
|
DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-W1052981D
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-172485A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
- HY-172275C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
|
- HY-182099B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG3400-DHLASLWWGTEL can be used for drug delivery .
|
- HY-177204B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
- HY-W1123942B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Silane is a multifunctional biomaterial that combines phospholipid DSPE, PEG and silane for drug delivery .
|
- HY-182092C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG3400-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
- HY-182097A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-177205B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG3400-CGKRK can be used for drug delivery .
|
- HY-182094B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG3400-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
|
- HY-182095B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG3400-CTP can be used for drug delivery .
|
- HY-172488A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
|
- HY-172690A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
- HY-182096B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG3400-KTP can be used for drug delivery .
|
- HY-172491A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-182098B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG3400-GALA can be used for drug delivery .
|
- HY-174896B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
|
- HY-W440906
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
|
- HY-172466A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
- HY-172270C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5112A
-
|
Azido-PEG3-FLAG TFA
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
|
-
- HY-P5112
-
|
Azido-PEG3-FLAG
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
|
-
- HY-169089
-
|
|
Drug Derivative
|
Cancer
|
|
RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
|
-
- HY-P11270
-
|
BGM0504; BG128
|
Insulin Receptor
GLP Receptor
|
Metabolic Disease
|
|
Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
|
-
- HY-169089A
-
|
|
Drug Derivative
|
Cancer
|
|
RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
|
-
- HY-P10319
-
|
|
PKA
|
Cardiovascular Disease
Cancer
|
|
RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
|
-
- HY-P11488
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P11485
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440881
-
|
|
|
DBCO
|
|
DSPE-PEG3400-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-DBCO sodium can be used in drug delivery research .
|
-
- HY-W440833
-
|
|
|
Azide
|
|
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.
|
-
- HY-P5112A
-
|
Azido-PEG3-FLAG TFA
|
|
Azide
|
|
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
|
-
- HY-P5112
-
|
Azido-PEG3-FLAG
|
|
Azide
|
|
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
|
-
- HY-W440835D
-
|
|
|
DBCO
|
|
DSPE-PEG3400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG3400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W440881A
-
|
|
|
DBCO
|
|
DSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-143209B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency .
|
-
- HY-W440916
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440881
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-DBCO sodium can be used in drug delivery research .
|
-
- HY-W441009A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W440833
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.
|
-
- HY-172279C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
|
-
- HY-172699A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
|
-
- HY-W440886
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
|
-
- HY-W440912
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG3400-Cy5 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-172470A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
-
- HY-172494A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
|
-
- HY-172273C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
|
-
- HY-172278C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-172681A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
|
-
- HY-172482A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
|
-
- HY-172687A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172684A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
-
- HY-172696A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
|
-
- HY-172726A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
|
-
- HY-172277C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
|
-
- HY-172280C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
|
-
- HY-172708A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-172464A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
|
-
- HY-172702A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
-
- HY-172476A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
|
-
- HY-172723A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
-
- HY-144000D
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-PDP ammonium is a phospholipid-PEG conjugate for drug delivery .
|
-
- HY-172503A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-179677A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG3400-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
|
-
- HY-W440881A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research .
|
-
- HY-172497A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
-
- HY-172479A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
|
-
- HY-176509B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
|
-
- HY-W440892
-
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Pegylated Lipids
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DSPE-PEG3400-OH is an amphiphilic polydisperse PEG which can spontaneously self-assemble in aqueous solution. The polymer can be used to prepare liposoome for targeted drug delivery.
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- HY-W440897
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Pegylated Lipids
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DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
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- HY-172711A
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Pegylated Lipids
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DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
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- HY-172473A
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Pegylated Lipids
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DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
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- HY-W440920
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG3400-Rhodamine is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-172276C
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Pegylated Lipids
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DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
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- HY-W440909
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG3400-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-172485A
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Pegylated Lipids
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DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
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- HY-172275C
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Pegylated Lipids
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DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
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- HY-172488A
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Pegylated Lipids
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DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
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- HY-W440906
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Pegylated Lipids
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DSPE-PEG3400-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
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- HY-172270C
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Pegylated Lipids
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DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
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