7 Results for "

Hepa 1c1c7

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Hepa 1c1c7" in MCE Product Catalog:

Cat. No.: HY-147128
CAS No.: 2378039-23-5
PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109's EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis .
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Cat. No.: HY-N10344
CAS No.: 67920-64-3
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .
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Cat. No.: HY-N6802
CAS No.: 66069-55-4
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent .
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Cat. No.: HY-167694
CAS No.: 856435-40-0
Target:  

Quinone Reductase

Research Areas:  

Cancer

Antiproliferative agent-62 (compound 5) is a functionalized benzylidene-indolin-2-one with notable antiproliferative activity and NQO1 activity induciton funciton, particularly in inducing NQO1 expression in murine Hepa1c1c7 cells and demonstrating effectiveness against human cancer cell lines, including MCF-7 and HCT116.
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Cat. No.: HY-N17587
CAS No.: 625434-15-3
3,24-Diacetate barbinervic acid is a triterpenoid derivative found in the stems of Coussarea brevicaulis .
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Cat. No.: HY-N11855
CAS No.: 477-89-4
Casimiroin is a QR2 and Aromatase inhibitor, with an IC50 of 54.1 μM against QR2 and an IC50 of 3.92 μM against aromatase. Casimiroin exhibits antimutagenic activity and inhibits DMBA (HY-W011845)-induced mutations in Salmonella typhimurium. Casimiroin suppresses DMBA-induced precancerous lesions in mouse mammary organ cultures. Casimiroin can be used in breast cancer-related research .
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Cat. No.: HY-177543
CAS No.: 65490-84-8
Target:  

Quinone Reductase

Research Areas:  

Others

5-(4-Methoxyphenol)-4-methyl-3H-1,2-dithiole-3-thione is a Phase 2 enzyme inducer. 5-(4-Methoxyphenol)-4-methyl-3H-1,2-dithiole-3-thione induces the activity of NAD (P) H:quinone oxidoreductase (QR; NQO1) in hepatoma cells. 5-(4-Methoxyphenol)-4-methyl-3H-1,2-dithiole-3-thione enhances growth hormone production in plasmid-transfected hepatoma cells .
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