PY109
Based on 1 Customer Validation
PY109 is an orally active AHR agonist with anti-inflammatory activity. PY109 promotes the production of the pro-inflammatory cytokines IL‑17A and IL‑22, and reduces disease severity in a mouse colitis model. PY109 can be used for colitis-related research.
For research use only. We do not sell to patients.
- Purity : 99.15%
- CAS No.: 2378039-23-5
- Formula: C15H9F3N2O
- Molecular Weight:290.24
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
|
IL-22 |
IL-17A |
In Vitro
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2378039-23-5
-
Appearance Solid
-
Molecular Weight 290.24
-
Formula C15H9F3N2O
-
Color Off-white to light yellow
-
SMILES
O=C(C1=CNC2=C1C=CC=C2)C3=NC(C(F)(F)F)=CC=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (344.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (299 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4454 mL | 17.2271 mL | 34.4542 mL | 86.1356 mL |
| 5 mM | 0.6891 mL | 3.4454 mL | 6.8908 mL | 17.2271 mL | |
| 10 mM | 0.3445 mL | 1.7227 mL | 3.4454 mL | 8.6136 mL | |
| 15 mM | 0.2297 mL | 1.1485 mL | 2.2969 mL | 5.7424 mL | |
| 20 mM | 0.1723 mL | 0.8614 mL | 1.7227 mL | 4.3068 mL | |
| 25 mM | 0.1378 mL | 0.6891 mL | 1.3782 mL | 3.4454 mL | |
| 30 mM | 0.1148 mL | 0.5742 mL | 1.1485 mL | 2.8712 mL | |
| 40 mM | 0.0861 mL | 0.4307 mL | 0.8614 mL | 2.1534 mL | |
| 50 mM | 0.0689 mL | 0.3445 mL | 0.6891 mL | 1.7227 mL | |
| 60 mM | 0.0574 mL | 0.2871 mL | 0.5742 mL | 1.4356 mL | |
| 80 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 1.0767 mL | |
| 100 mM | 0.0345 mL | 0.1723 mL | 0.3445 mL | 0.8614 mL |
PY109 Related Classifications
HY-147128 Related Classifications
Powered by Bioz