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Hyaluronoglucosaminidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glycosidase (1) NF-κB (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-107910

Hyaluronidase, Bovine testes 15+ Cited Publications Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes	NF-κB	Inflammation/Immunology Cancer
Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection .

HY-P991212

Berahyaluronidase alfa ALT-B4	Glycosidase	Cancer
Berahyaluronidase alfa (ALT-B4) is a recombinant hyaluronidase engineered from human hyaluronidase PH20. Berahyaluronidase alfa features favorable structural stability and enzymatic activity, and can be used to enhance drug absorption and dispersion in subcutaneous or intradermal administration .

Cat. No.	Nombre del producto	Target	Research Area	Image

HY-P991212

Berahyaluronidase alfa ALT-B4	Glycosidase	Cancer
Berahyaluronidase alfa (ALT-B4) is a recombinant hyaluronidase engineered from human hyaluronidase PH20. Berahyaluronidase alfa features favorable structural stability and enzymatic activity, and can be used to enhance drug absorption and dispersion in subcutaneous or intradermal administration .

Species:	Human (3) Mouse (1)
Tag:	His (4)
Source:	HEK293 (4)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P79066

	*Hyaluronidase 2/HYAL2 Protein, Human (HEK293, His)* Hyaluronidase 2; LUCA2; LuCa-2; Hyaluronoglucosaminidase 2; Lung Carcinoma Protein 2; Lysosomal Hyaluronidase; Hyaluronoglucosaminidase-2	Human	HEK293
	Hyaluronidase 2 (HYAL2) protein participates in the hydrolysis of high molecular weight hyaluronic acid, generating intermediate-sized products. Despite low activity, HYAL2 contributes to extracellular matrix dynamics through hyaluronic acid breakdown. Furthermore, it associates with and negatively regulates MST1R, suggesting a potential role in cellular processes mediated by MST1R. Hyaluronidase 2/HYAL2 Protein, Human (HEK293, His) is the recombinant human-derived Hyaluronidase 2/HYAL2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P703763

	*Hyaluronidase 2/HYAL2 Protein, Mouse (HEK293, His)* Hyaluronidase-2; Hyaluronoglucosaminidase-2; Hyal2; Hyal-2	Mouse	HEK293
	Hyaluronidase 2/HYAL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Hyaluronidase 2/HYAL2 protein, expressed by HEK293, with C-His tag.

HY-P70411

	*Hyaluronidase-1/HYAL1 Protein, Human (HEK293, His, solution)* 1 Publications Verification rHuHyaluronidase-1/HYAL1, His; Hyaluronidase-1; Hyal-1; Hyaluronoglucosaminidase-1; Lung Carcinoma Protein 1; LuCa-1; HYAL1; LUCA1	Human	HEK293
	Hyaluronidase-1/HYAL1 Protein is implicated in tumor progression, suggesting its role in cancer advancement. It also inhibits TGFB1-enhanced cell growth, revealing its regulatory function. HYAL1's dual impact on promoting tumor progression and inhibiting specific cellular processes underscores its complex involvement in cellular behavior and potential significance in tumorigenesis. Hyaluronidase-1/HYAL1 Protein, Human (HEK293, His, solution) is the recombinant human-derived Hyaluronidase-1/HYAL1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70411A

	*Hyaluronidase-1/HYAL1 Protein, Human (HEK293, C-His)* rHuHyaluronidase-1/HYAL1, His; Hyaluronidase-1; Hyal-1; Hyaluronoglucosaminidase-1; Lung Carcinoma Protein 1; LuCa-1; HYAL1; LUCA1	Human	HEK293
	Hyaluronidase-1/HYAL1 Protein is implicated in tumor progression, suggesting its role in cancer advancement. It also inhibits TGFB1-enhanced cell growth, revealing its regulatory function. HYAL1's dual impact on promoting tumor progression and inhibiting specific cellular processes underscores its complex involvement in cellular behavior and potential significance in tumorigenesis. Hyaluronidase-1/HYAL1 Protein, Human (HEK293, C-His) is the recombinant human-derived Hyaluronidase-1/HYAL1, expressed by HEK293, with C-6His labeled tag. The total length of Hyaluronidase-1/HYAL1 Protein, Human (HEK293, C-His) is 414 a.a.*.

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HY-P86254

	SPAM1 Antibody (YA5946) SPAM1; HYAL3; PH20; Hyaluronidase PH-20 ; Hyal-PH20; Hyaluronoglucosaminidase PH-20; Sperm adhesion molecule 1; Sperm surface protein PH-20;	WB, IHC-P	Human
	SPAM1 Antibody (YA5946) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SPAM1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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