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Results for "

MSI

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Peptides

3

Natural
Products

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16468
    Squalamine

    MSI-1256

    		 Bacterial HBV Infection Cancer
    Squalamine(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.
    Squalamine
  • HY-105088
    Pexiganan

    MSI 78 free base

    		 Bacterial Infection
    Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections .
    Pexiganan
  • HY-12219B
    MSI-1701

    		Others Metabolic Disease
    MSI-1701 is an analogue of MSI-1436 which can control weight gain and blood glucose level extracted from patent US 7410959 B1.
    <em>MSI</em>-1701
  • HY-12219
    MSI-1436

    Trodusquemine; Aminosterol-1436

    		 Phosphatase Endocrinology
    MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of appr 1 μM, 200-fold preference over TCPTP (IC50, 224 μM).
    <em>MSI</em>-1436
  • HY-RS08714
    MSI1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MSI1 Human Pre-designed siRNA Set A contains three designed siRNAs for MSI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MSI1 Human Pre-designed siRNA Set A
    MSI1 Human Pre-designed siRNA Set A
  • HY-RS08715
    MSI2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MSI2 Human Pre-designed siRNA Set A contains three designed siRNAs for MSI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MSI2 Human Pre-designed siRNA Set A
    MSI2 Human Pre-designed siRNA Set A
  • HY-12219A
    MSI-1436 lactate
    1 Publications Verification

    Trodusquemine lactate; Aminosterol-1436 lactate

    		 Phosphatase Endocrinology
    MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
    <em>MSI</em>-1436 lactate
  • HY-16467
    Squalamine lactate

    MSI-1256F

    		 Bacterial Infection Cardiovascular Disease Cancer
    Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
    Squalamine lactate
  • HY-108466
    Ro 08-2750
    2 Publications Verification

    		 Apoptosis Neurological Disease Cancer
    Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 inhibits NGF binding to p75 NTR selectively over TRKA . Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM .
    Ro 08-2750
  • HY-121515
    DPM-1001

    		Phosphatase Metabolic Disease
    DPM-1001 is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM. DPM-1001 is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 has anti-diabetic property .
    DPM-1001
  • HY-121515A
    DPM-1001 trihydrochloride

    		Phosphatase Metabolic Disease
    DPM-1001 trihydrochloride is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM. DPM-1001 trihydrochloride is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 trihydrochloride has anti-diabetic property .
    DPM-1001 trihydrochloride
  • HY-119734
    Gossypolone

    		Others Cancer
    Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer .
    Gossypolone
  • HY-161386
    WRN inhibitor 7

    		DNA/RNA Synthesis Cancer
    WRN inhibitor 7 (Compound h6) is a WRN inhibitor. WRN inhibitor 7 effectively inhibits WRN's helicase and ATPase activity (IC50: 9.8 μM and 15.8 μM respectively). WRN inhibitor 7 can be used for research of microsatellite instable (MSI) cancers .
    WRN inhibitor 7
  • HY-158116
    VVD-214

    RO7589831; VVD-133214

    		 DNA/RNA Synthesis Cancer
    VVD-214 is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers.
    VVD-214

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