Musashi 2 Antibody (YA3045)
(Synonyms: MSI2; RNA-binding protein Musashi homolog 2; Musashi-2)Musashi 2 Antibody (YA3045) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Musashi 2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:200 | 1:50-1:100 |
Product Details
Musashi 2 Antibody (YA3045) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Musashi 2.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 35 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 35 kDa
Entrez Gene: 124540 Human ; 76626 Mouse ; 360596 Rat
SwissProt: Q96DH6 Human ; Q920Q6 Mouse ;
OMIM: 607897 Human
A synthesized peptide derived from human MSI2 aa200-280.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Musashi 2 is a RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system
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Subcellular Localization
Cytoplasm
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Expression
Tissue_specificity:It is ubiquitous; it can be detected even at low concentrations.
Induction:Up-regulated in astrocytes after brain injury -
Isoforms & Post-Translational Modification
Q96DH6 has 3 isomers: Q96DH6-1: 35197 Da (predicted); Q96DH6-2: 28421 Da (predicted); Q96DH6-3: 17238 Da (predicted).
Phosphorylated. Ubiquitinated by the RHOBTB2-CUL3-RBX1 ubiquitin ligase complex (PubMed:27941885) -
Subunit
Interacts with RHOBTB2; the interaction is necessary for MSI2 ubiquitination and degradation
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SwissProt ID
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Synonyms
MSI2; RNA-binding protein Musashi homolog 2; Musashi-2
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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