Gossypolone
Based on 1 Customer Validation
Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 96.28%
- CAS No.: 4547-72-2
- Formula: C30H26O10
- Molecular Weight:546.52
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Musashi-1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
23.3 μM
Compound: 13, gossypolone
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Anticancer activity against human HeLa cells after 48 hrs by MTT assay
Anticancer activity against human HeLa cells after 48 hrs by MTT assay
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[PMID: 19447525] |
| U-87MG ATCC | IC50 |
26.1 μM
Compound: 13, gossypolone
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Anticancer activity against human U87 cells after 48 hrs by MTT assay
Anticancer activity against human U87 cells after 48 hrs by MTT assay
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[PMID: 19447525] |
Chemical Information
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CAS No. 4547-72-2
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Appearance Solid
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Molecular Weight 546.52
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Formula C30H26O10
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Color Light yellow to brown
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SMILES
O=CC1=C(C(O)=C(C2=C1C(C(C(C3=O)=C(C(C4=C3C(C=O)=C(C(O)=C4C(C)C)O)=O)C)=C(C2=O)C)=O)C(C)C)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gossypolone Related Classifications
HY-119734 Related Classifications
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