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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Molecular hybridization
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Molecular hybridization" in MCE Product Catalog:
Cat. No.: HY-W012954B
CAS No.: 75-57-0
Synonyms: Tetramethylammonium chloride, for Molecular biology, 99%(T)
Cat. No.: HY-21286
CAS No.: 63264-29-9
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N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .
Cat. No.: HY-162349
CAS No.: 3030144-11-4
PARP7/HDACs-IN-1 (compound 9l) is a dual-target inhibitor targeting PARP7/HDAC with anti-tumor activity. PARP7/HDACs-IN-1 inhibits different subtypes of PARPs and HDACs with IC50s of 83.3 nM (PARP1), 3.1 nM (PARP7), 35 nM (HDAC1), 30.3 nM (HDAC2), 35.4 nM (HDAC3), and 6.4 nM respectively. (HDAC6) . br/ .
Cat. No.: HY-180811
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ALK/HDAC-IN-2 (Compound 19b) is an ALK/HDAC inhibitor with IC₅₀ values for ALK WT and total HDACs of 8 nM and 1.18 μM, respectively. ALK/HDAC-IN-2 exhibits inhibitory activity against ALK mutants G1202R, F1174L, and L1196M, with IC₅₀ values of 2.74, 9.23, and 34.28 nM, respectively. ALK/HDAC-IN-2 shows potent and selective inhibition against HDAC1 (IC₅₀ = 0.24 μM), while its inhibitory activity against HDAC7, HDAC6, and HDAC11 is weak (IC₅₀ > 10 μM). ALK/HDAC-IN-2 has broad-spectrum anti-proliferative activity against various cancer cells, inducing cell cycle arrest and apoptosis. ALK/HDAC-IN-2 can be used for the study of neuroblastoma .
Cat. No.: HY-179619
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Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor. Its IC50 values for L-dopa and L-tyrosine are 3.24 and 2.79 nM respectively. Tyrosinase-IN-46 inhibits melanin synthesis and shows a significant anti-pigmentation effect. Tyrosinase-IN-46 can be used for the study of pigmentation disorders .
Cat. No.: HY-W1061733
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TAO-F Phosphoramidite is a type of phosphoramidite monomer that can be used for solid-phase synthesis of oligonucleotides. TAO-F Phosphoramidite is used to prepare fluorescent-labeled probes and primers, and is widely applied in real-time quantitative PCR (qPCR), fluorescence in situ hybridization (FISH), and microarray molecular diagnostic techniques.
Cat. No.: HY-W665456
CAS No.: 959151-70-3
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Cat. No.: HY-P11680
CAS No.: 253438-99-2
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Cat. No.: HY-W540123
CAS No.: 186046-82-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
