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Nicotinamide phosphoribosyl transferase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NAMPT (3) Apoptosis (1) Phosphodiesterase (PDE) (1)
By Research Areas:	Cancer (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Targets Recommended: NAMPT γ-Glutamyl Transferase (GGT) Farnesyl Transferase GGTase Glutathione S-transferase OGT

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-12628

GNE-618 2 Publications Verification	NAMPT	Cancer
GNE-618 is a potent, orally active nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with an IC₅₀ of 6 nM. GNE-618 depletes NAD levels and induces tumor cell death. Anti-tumor activity .

HY-10080

Teglarinad chloride GMX1777; EB-1627	NAMPT	Cancer
Teglarinad chloride (GMX1777) is a proagent of GMX1778 (a nicotinamide phosphoribosyl transferase inhibitor). Teglarinad chloride exhibits antitumor activity in mice can be attributed to inhibition of NAMPT. Teglarinad chloride also enhances radiation efficacy, mediated by interference with DNA repair and antiangiogenesis .

HY-172919

PDEδ/NAMPT IN-1	Phosphodiesterase (PDE) NAMPT Apoptosis	Cancer
PDEδ/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) (K_D=0.410 nM) and nicotinamide phosphoribosyl transferase (NAMPT) (IC₅₀=2.21 nM). PDEδ/NAMPT IN-1 blocks KRAS-related signal transduction and interferes with the synthesis of nicotinamide adenine dinucleotide (NAD ⁺), inducing apoptosis in KRAS mutant pancreatic cancer cells. PDEδ/NAMPT IN-1 is promising for research of KRAS mutant pancreatic cancer .

Species:	Human (2) Mouse (2)
Tag:	SUMO (1) His (2) Strep (1) Tag Free (1) GST (1) Flag (1)
Source:	Sf9 insect cells (1) P. pastoris (1) E. coli (2)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P701315

	NAMPT Protein, Mouse (P.pastoris, His) rHuNicotinamide phosphoribosyltransferase/NAMPT, His; Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1	Mouse	P. pastoris
	NAMPT protein has dual functions of cytokine and adipokine. Due to limited ATP activation, its secreted form lacks enzymatic activity. It catalyzes the condensation of nicotinamide and 5-phosphoribosyl-1-pyrophosphate to produce nicotinamide mononucleotide, which is critical for NAD biosynthesis. NAMPT Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived NAMPT protein, expressed by P. pastoris , with N-10*His labeled tag.

HY-P701314

	NAMPT Protein, Mouse 3 Publications Verification rHuNicotinamide phosphoribosyltransferase/NAMPT, His; Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1	Mouse	E. coli
	NAMPT protein has dual functions of cytokine and adipokine. Due to limited ATP activation, its secreted form lacks enzymatic activity. It catalyzes the condensation of nicotinamide and 5-phosphoribosyl-1-pyrophosphate to produce nicotinamide mononucleotide, which is critical for NAD biosynthesis. NAMPT Protein, Mouse is the recombinant mouse-derived NAMPT protein, expressed by E. coli , with tag free.

HY-P704014

	NAMPT Protein, Human (sf9, His, GST) rHuNicotinamide phosphoribosyltransferase/NAMPT, His; Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1	Human	Sf9 insect cells
	NAMPT protein catalyzes the synthesis of nicotinamide mononucleotide, a key intermediate in NAD biosynthesis. NAMPT Protein, Human (sf9, His, GST) is the recombinant human-derived NAMPT protein, expressed by Sf9 insect cells, with N-His and N-GST labeled tag.

HY-P70353

	NAMPT Protein, Human (His) 4 Publications Verification rHuNicotinamide phosphoribosyltransferase/NAMPT, His; Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1	Human	E. coli
	NAMPT protein catalyzes the synthesis of nicotinamide mononucleotide, a key intermediate in NAD biosynthesis. NAMPT Protein, Human (His) is the recombinant human-derived NAMPT protein, expressed by E. coli , with N-6*His labeled tag.

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Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Mouse (2) Rat (2) Monkey (2) Rabbit (2)
Application:	IHC-P (4) ICC/IF (2) WB (2) FC (2) ELISA (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P85319

	Visfatin Antibody (YA5011) NAMPT; PBEF; PBEF1; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin	WB, IHC-P, ICC/IF, FC, ELISA	Human, Rat, Mouse, Monkey, Rabbit
	Visfatin Antibody (YA5011) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Visfatin.

HY-P85319A

	Visfatin Antibody (YA5011)(PBS only) NAMPT; PBEF; PBEF1; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin	WB, IHC-P, ICC/IF, FC, ELISA	Human, Rat, Mouse, Monkey, Rabbit
	Visfatin Antibody (YA5011) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Visfatin.

HY-P81438

	Visfatin Antibody (YA1183) Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin	IHC-P	Human
	Visfatin Antibody (YA1183) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Visfatin.

HY-P81438A

	Visfatin Antibody (YA1183)(PBS only) Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin	IHC-P	Human
	Visfatin Antibody (YA1183) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Visfatin.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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