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Results for "

PME

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108317
    ABL127

    		Phosphatase Cancer
    ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively.
    ABL127
  • HY-12833
    AMZ30
    1 Publications Verification

    		 Phosphatase Akt ERK Others
    AMZ30 is selective protein phosphatase methylesterase-1(PME-1) inhibitor with IC50s of 600 nM and 3.5 µM in human cell lysates and in HEK 293T cells, respectively. AMZ30 shows >100-fold selectivity relative to other serine hydrolases. AMZ30 reduces the demethylated form of PP2A in living cells. AMZ30 attenuates muscle cell differentiation. AMZ30 increases the resistance of U87MG and U251MG glioblastoma cells to t-BHP-induced oxidative stress. AMZ30can be used for the study of glioblastoma .
    AMZ30
  • HY-174370
    MePT-S-N-Pme

    		SARS-CoV Infection
    MePT-S-N-Pme is an inhibitor of SARS-CoV-2 RdRp activity. MePT-S-N-Pme demonstrates a significant reduced reporter activity with an IC50 of 7 μM in HEK 293 cells. MePT-S-N-Pme has a slight inhibitory effect on nucleotidyltransferase activity. MePT-S-N-Pme significantly inhibits SARS-CoV-2 replication in vitro .
    MePT-S-N-Pme
  • HY-RS03272
    CSTB Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CSTB Human Pre-designed siRNA Set A contains three designed siRNAs for CSTB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CSTB Human Pre-designed siRNA Set A
    CSTB Human Pre-designed siRNA Set A

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