PPME1 Antibody (YA7962)(PBS only)
(Synonyms: PME-1)PPME1 Antibody (YA7962) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PPME1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:50-250 | 1:100-250 | 1:100 |
Product Details
PPME1 Antibody (YA7962) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PPME1.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 42.3 kDa
Full length human recombinant protein of human PPME1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PPME1 is a Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme
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Isoforms & Post-Translational Modification
Q9Y570 has four isomers: Q9Y570-1: 42315 Da (predicted); Q9Y570-2: 22462 Da (predicted); Q9Y570-3: 18214 Da (predicted); Q9Y570-4: 43870 Da (predicted).
Phosphorylated by SIK1 following increases in intracellular sodium, leading to dissociation from the protein phosphatase 2A (PP2A) complex and subsequent dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 -
Subunit
Binds PPP2CA and PPP2CB
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SwissProt ID
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Synonyms
PME-1
Documentation
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