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SLB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Beta-lactamase (1) Biochemical Assay Reagents (1) Fluorescent Dye (1) Liposome (1) LPL Receptor (4) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (4)
Oligonucleotides:	Phospholipids (1) Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5366

PEP1	Liposome	Others
PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions .

HY-150254A

SLB1122168 formic 1 Publications Verification	LPL Receptor	Inflammation/Immunology
SLB1122168 formic is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 formic inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC₅₀ of 94 nM. SLB1122168 formic induces lymphopenia in circulating lymphocytes in mice and rats .

HY-150254

SLB1122168	LPL Receptor	Inflammation/Immunology
SLB1122168 is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC₅₀ of 94 nM. SLB1122168 induces lymphopenia in circulating lymphocytes in mice and rats .

HY-145502

1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium	Biochemical Assay Reagents	Others
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .

HY-RS06600

IFT172 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IFT172 Human Pre-designed siRNA Set A contains three designed siRNAs for IFT172 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IFT172 Human Pre-designed siRNA Set A IFT172 Human Pre-designed siRNA Set A

HY-182375A

SLB1122168 free base	LPL Receptor	Inflammation/Immunology Cancer
SLB1122168 free base is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 free base inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC₅₀ of 94 nM. SLB1122168 free base induces lymphopenia in circulating lymphocytes in mice and rats .

HY-182375

*(R)-SLB1122168 free base*	LPL Receptor	Inflammation/Immunology
(R)-SLB1122168 free base, an isomer of SLB1122168 free base (HY-182375A), is a spinster homolog 2 (SPNS2) inhibitor with an IC₅₀ ≤2 μM .

HY-178975

β-Lactamase-IN-10	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-10 (Compound CB1) is a dual-metal β-lactamase (MLB) and serine β-lactamase *(SLB)* inhibitor. β-Lactamase-IN-10 exhibits antibacterial (antibacterial) activity against various drug-resistant bacteria. β-Lactamase-IN-10 can be used in the research of Gram-negative superbug infections .

HY-203233

Rhodamine-DHPE	Fluorescent Dye	Others
Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu ²⁺-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy .

Cat. No.	Product Name	Type

HY-203233

Rhodamine-DHPE	Fluorescent Dyes
Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu ²⁺-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy .

Rhodamine-DHPE

Fluorescent Dyes

Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu ²⁺-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy .

Cat. No.	Product Name	Target	Research Area

HY-P5366

PEP1	Liposome	Others
PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions .

Cat. No.	Product Name		Classification

HY-145502

1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium		Phospholipids
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .

HY-RS06600

IFT172 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
IFT172 Human Pre-designed siRNA Set A contains three designed siRNAs for IFT172 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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