(R)-SLB1122168 free base
(R)-SLB1122168 free base, an isomer of SLB1122168 free base (HY-182375A), is a spinster homolog 2 (SPNS2) inhibitor with an IC50 ≤2 μM.
For research use only. We do not sell to patients.
- CAS No.: 2764877-97-4
- Formula: C22H35N3O
- Molecular Weight:357.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
S1PR1 |
In Vitro
(R)-SLB1122168 free base (Compound 38) inhibits mouse SPNS2 in HeLa cells with an IC50 ≤2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Parmacokinetics
| Species | Dose | Route | Cmax | Tmax | T1/2 |
|---|---|---|---|---|---|
| Rat[1] | 10 mg/kg | i.p. | 4 μM | 2 h | 8 h |
Chemical Information
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CAS No. 2764877-97-4
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Molecular Weight 357.53
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Formula C22H35N3O
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SMILES
CCCCCCCCCCC1=CC=C2OC(NC[C@@H]3CCNC3)=NC2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-SLB1122168 free base Related Classifications
HY-182375 Related Classifications
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