2. Signaling Pathways
  3. GPCR/G Protein
  4. LPL Receptor
  5. S1PR5 Isoform

S1PR5

 

S1PR5 Related Products (12):

Cat. No. Product Name Effect Purity
  • HY-12355
    Siponimod
    		Agonist 98.88%
    Siponimod (BAF-312) is an orally active and selective sphingosine-1-phosphate (S1P) receptor modulator.
  • HY-12288
    Ozanimod
    		Agonist 99.83%
    Ozanimod (RPC-1063), a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5).
  • HY-10569
    Ponesimod
    		Agonist 99.81%
    Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay.
  • HY-17606
    Cenerimod
    		Agonist 98.02%
    Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM.
  • HY-136578
    RP101988
    		Agonist 98.92%
    RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely.
  • HY-148198
    S1P5 receptor agonist-1
    		Agonist
    S1P5 receptor agonist-1 (example 6) is a potent and selective agonist of S1P5 receptor with an EC50 value of 20 nM.
  • HY-136576
    RP101075
    		Agonist
    RP101075, an active metabolite of Ozanimod, is a potent, orally active S1PR (sphingosine-1-phosphate receptor 1) agonist, with an EC50 of 0.27 nM.
  • HY-12355A
    Siponimod hemifumarate
    		Agonist
    Siponimod (BAF-312) hemifumarate is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator.
  • HY-148115
    S1p receptor agonist 2
    		Agonist
    S1p receptor agonist 2 (compound 1) is an agonist of S1P5 receptor, exhibits selectivity over the S1P1 and/or S1P3 receptors.
  • HY-12288A
    Ozanimod hydrochloride
    		Modulator
    Ozanimod (RPC-1063) hydrochloride, a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5).
  • HY-111253
    CYM-5478
    		Agonist
    CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay.
  • HY-136577
    RP101442
    		Agonist
    RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively.