S1P5 receptor agonist-1
S1P5 receptor agonist-1 (Example 6) is an effective and selective S1P5 receptor (S1P5 receptor) agonist. The EC50 values for S1P5 and S1P1 receptors are 20 nM and > 3 μM, respectively. S1P5 receptor agonist-1 can be used in studies on neuroprotection and immune regulation.
For research use only. We do not sell to patients.
- CAS No.: 2373330-78-8
- Formula: C20H24F3NO3
- Molecular Weight:383.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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S1PR5 20 nM (EC50) |
S1P5 is a target with dual properties: In multiple sclerosis, it exhibits significant neuroprotective effects by promoting myelin regeneration and inhibiting the infiltration of inflammatory cells. In tumor immunotherapy, by regulating the functions of NK cells and monocytes, it is expected to enhance anti-tumor immunity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2373330-78-8
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Molecular Weight 383.40
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Formula C20H24F3NO3
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SMILES
FC(F)(F)CCCOC1=CC=C(C=C([C@H](C2)C)CN3CC(C3)C(O)=O)C2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
S1P5 receptor agonist-1 Related Classifications
HY-148198 Related Classifications
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