1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. LPL Receptor
    Drug Metabolite
  3. RP101442

RP101442 

Cat. No.: HY-136577
Handling Instructions

RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively.

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RP101442 Chemical Structure

RP101442 Chemical Structure

CAS No. : 1306761-08-9

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Description

RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].

IC50 & Target[1]

S1PR1

2.6 nM (EC50)

S1PR5

171 nM (EC50)

Molecular Weight

402.45

Formula

C₂₃H₂₂N₄O₃

CAS No.

1306761-08-9

SMILES

CC(N[[email protected]]1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

RP101442RP 101442RP-101442LPL ReceptorDrug MetaboliteLysophospholipid ReceptorselectiveulcerativecolitismetaboliteInhibitorinhibitorinhibit

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RP101442
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