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Results for "

acetylenic compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (15) E3 Ligase Ligand-Linker Conjugates (1) Lipoxygenase (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (2)
Click Chemistry:	Azide (7)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-129608

Lenalidomide-acetylene-C5-COOH Cereblon ligand-linker Conjugate	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC . Lenalidomide-acetylene-C5-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W016961

Bis(trimethylsilyl)acetylene	Biochemical Assay Reagents	Others
Bis(trimethylsilyl)acetylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-N3941

Ginsenoyne K	Others	Others
Ginsenoyne K (compound 3) is an acetylenic compound that can be isolated from the roots of Panax ginseng .

HY-N2889

Arctinol B	Others
Arctinol B is a sulfur-containing acetylenic compound that can be isolated from the roots of Arctium lappa L .

HY-14988

I-A09	Bacterial	Infection
I-A09 and its derivatives, specifically 1,2,3-triazole-adamantylacetamide hybrids (5a–u), exhibit significant antitubercular activity. These hybrids were synthesized using copper-catalyzed click chemistry, combining bioactive fragments from antitubercular I-A09 and substituted adamantyl urea. The compound N-(1-adamantyl)-2-azido acetamide was reacted with various alkyl/aryl acetylenes to produce new analogues. Among them, N-(1-adamantan-1-yl)-2-(4-(phenanthren-2-yl)-1H-1,2,3-triazol-1-yl)acetamide (5t) showed the most promise with a minimum inhibitory concentration (MIC) of 3.12 μg/mL against Mycobacterium tuberculosis H37Rv, and a selectivity index greater than 15 .

HY-N18235

(1Z)-Atractylodinol	Lipoxygenase	Inflammation/Immunology
(1Z)-Atractylodinol, an acetylenes compound, is a weak 5-lipoxygenase (5-LOX) inhibitor with an IC₅₀ of 17.8 μM. (1Z)-Atractylodinol can be used for the study of inflammatory diseases .

HY-N18147

(3R,4S,5E,11E)-1,5,11-Tridecatriene-7,9-diyne-3,4-diol	Others	Others
(3R,4S,5E,11E)-1,5,11-Tridecatriene-7,9-diyne-3,4-diol (compound CZ-6) is a polyene acetylene compound with significant inhibitory effects on BMM cells .

HY-W1051916C

NH2-PEG5000-DBCO	Biochemical Assay Reagents	Others
NH2-PEG5000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG5000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916A

NH2-PEG2000-DBCO	Biochemical Assay Reagents	Others
NH2-PEG2000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG2000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916H

NH2-PEG400-DBCO	Biochemical Assay Reagents	Others
NH2-PEG400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916B

NH2-PEG3400-DBCO	Biochemical Assay Reagents	Others
NH2-PEG3400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG3400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916I

NH2-PEG600-DBCO	Biochemical Assay Reagents	Others
NH2-PEG600-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG600-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916

NH2-PEG1000-DBCO	Biochemical Assay Reagents	Others
NH2-PEG1000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG1000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916D

NH2-PEG10000-DBCO	Biochemical Assay Reagents	Others
NH2-PEG10000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG10000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-179193E

Azide-PEG5000-OPSS N3-PEG5000-OPSS	Biochemical Assay Reagents	Others
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193C

Azide-PEG2000-OPSS N3-PEG2000-OPSS	Biochemical Assay Reagents	Others
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193H

Azide-PEG10000-OPSS N3-PEG10000-OPSS	Biochemical Assay Reagents	Others
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193B

Azide-PEG1000-OPSS N3-PEG1000-OPSS	Biochemical Assay Reagents	Others
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193D

Azide-PEG3400-OPSS N3-PEG3400-OPSS	Biochemical Assay Reagents	Others
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193A

Azide-PEG600-OPSS N3-PEG600-OPSS	Biochemical Assay Reagents	Others
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193

Azide-PEG400-OPSS N3-PEG400-OPSS	Biochemical Assay Reagents	Others
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-N18146

14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol	Others	Inflammation/Immunology
14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is an orally active acetylenic compound present in the rhizomes of Atractylodes macrocephala Koidz. 14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is applicable to the research of acute inflammation .

Cat. No.	Product Name

HY-L036P

Covalent Screening Library Plus	5,994 compounds
Small molecule covalent inhibitors, or irreversible inhibitors, are a type of inhibitors that exert their biological functions by irreversibly binding to target through covalent bonds. Compared with non-covalent inhibitors, covalent inhibitors have obvious advantages in bioactivity, such that covalent warheads can target rare residues of a particular target protein, thus leading to the development of highly selective inhibitors and achieving a more complete and continued target occupancy in living systems. In recent years, the distinct strengths of covalent inhibitors in overcoming drug resistance had been recognized. However, toxicity can be a real challenge related to this class of therapeutics due to their potential for off-target reactivity and has led to these drugs being disfavored as a drug class. The drug design and optimization of covalent inhibitors has become a hot spot in drug discovery. MCE covalent inhibitor library contains 5,994 small molecules including identified covalent inhibitors and other molecules having common covalent reactive groups as warheads, such as acrylamides, activated terminal acetylenes, sulfonyl fluorides/esters, cloracetamides, alkyl halides, epoxides, aziridines, disulfides, etc. MCE Covalent inhibitor Library plus, with more powerful screening capability, further complement Covalent inhibitor Library (HY-L036) by adding some fragment compounds with covalent warheads.

Covalent Screening Library Plus

5,994 compounds

Small molecule covalent inhibitors, or irreversible inhibitors, are a type of inhibitors that exert their biological functions by irreversibly binding to target through covalent bonds. Compared with non-covalent inhibitors, covalent inhibitors have obvious advantages in bioactivity, such that covalent warheads can target rare residues of a particular target protein, thus leading to the development of highly selective inhibitors and achieving a more complete and continued target occupancy in living systems. In recent years, the distinct strengths of covalent inhibitors in overcoming drug resistance had been recognized. However, toxicity can be a real challenge related to this class of therapeutics due to their potential for off-target reactivity and has led to these drugs being disfavored as a drug class. The drug design and optimization of covalent inhibitors has become a hot spot in drug discovery.

MCE covalent inhibitor library contains 5,994 small molecules including identified covalent inhibitors and other molecules having common covalent reactive groups as warheads, such as acrylamides, activated terminal acetylenes, sulfonyl fluorides/esters, cloracetamides, alkyl halides, epoxides, aziridines, disulfides, etc.

MCE Covalent inhibitor Library plus, with more powerful screening capability, further complement Covalent inhibitor Library (HY-L036) by adding some fragment compounds with covalent warheads.

Cat. No.	Product Name	Type

HY-W016961

Bis(trimethylsilyl)acetylene	Biochemical Assay Reagents
Bis(trimethylsilyl)acetylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W1051916C

NH2-PEG5000-DBCO	Biochemical Assay Reagents
NH2-PEG5000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG5000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916A

NH2-PEG2000-DBCO	Biochemical Assay Reagents
NH2-PEG2000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG2000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916H

NH2-PEG400-DBCO	Biochemical Assay Reagents
NH2-PEG400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916B

NH2-PEG3400-DBCO	Biochemical Assay Reagents
NH2-PEG3400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG3400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916I

NH2-PEG600-DBCO	Biochemical Assay Reagents
NH2-PEG600-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG600-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916

NH2-PEG1000-DBCO	Biochemical Assay Reagents
NH2-PEG1000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG1000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-W1051916D

NH2-PEG10000-DBCO	Biochemical Assay Reagents
NH2-PEG10000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG10000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

HY-179193E

Azide-PEG5000-OPSS N3-PEG5000-OPSS	Biochemical Assay Reagents
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG5000-OPSS

N3-PEG5000-OPSS

Biochemical Assay Reagents

Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193C

Azide-PEG2000-OPSS N3-PEG2000-OPSS	Biochemical Assay Reagents
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG2000-OPSS

N3-PEG2000-OPSS

Biochemical Assay Reagents

Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193H

Azide-PEG10000-OPSS N3-PEG10000-OPSS	Biochemical Assay Reagents
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG10000-OPSS

N3-PEG10000-OPSS

Biochemical Assay Reagents

Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193B

Azide-PEG1000-OPSS N3-PEG1000-OPSS	Biochemical Assay Reagents
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG1000-OPSS

N3-PEG1000-OPSS

Biochemical Assay Reagents

Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193D

Azide-PEG3400-OPSS N3-PEG3400-OPSS	Biochemical Assay Reagents
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG3400-OPSS

N3-PEG3400-OPSS

Biochemical Assay Reagents

Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193A

Azide-PEG600-OPSS N3-PEG600-OPSS	Biochemical Assay Reagents
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG600-OPSS

N3-PEG600-OPSS

Biochemical Assay Reagents

Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193

Azide-PEG400-OPSS N3-PEG400-OPSS	Biochemical Assay Reagents
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azide-PEG400-OPSS

N3-PEG400-OPSS

Biochemical Assay Reagents

Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Ginsenoyne K	Panax ginseng C. A. Meyer Structural Classification Natural Products Plants Araliaceae Source Classification	Others
Ginsenoyne K (compound 3) is an acetylenic compound that can be isolated from the roots of Panax ginseng .

Arctinol B	Structural Classification Natural Products Rhaponticum uniflorum (L.) DC. Asteraceae Plants Compositae Caesalpinia magnifoliolata Metc. Source Classification	Others
Arctinol B is a sulfur-containing acetylenic compound that can be isolated from the roots of Arctium lappa L .

(1Z)-Atractylodinol	Structural Classification Natural Products Plants Compositae Source Classification Erythrina sigmoidea Hua	Lipoxygenase
(1Z)-Atractylodinol, an acetylenes compound, is a weak 5-lipoxygenase (5-LOX) inhibitor with an IC₅₀ of 17.8 μM. (1Z)-Atractylodinol can be used for the study of inflammatory diseases .

(3R,4S,5E,11E)-1,5,11-Tridecatriene-7,9-diyne-3,4-diol	Structural Classification Natural Products Plants Compositae Source Classification Erythrina sigmoidea Hua	Others
(3R,4S,5E,11E)-1,5,11-Tridecatriene-7,9-diyne-3,4-diol (compound CZ-6) is a polyene acetylene compound with significant inhibitory effects on BMM cells .

14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol	Structural Classification Natural Products Astragalus caprinus L. Plants Compositae Source Classification	Others
14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is an orally active acetylenic compound present in the rhizomes of Atractylodes macrocephala Koidz. 14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is applicable to the research of acute inflammation .

Cat. No.	Product Name		Classification

HY-179193E

Azide-PEG5000-OPSS N3-PEG5000-OPSS		Azide
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193C

Azide-PEG2000-OPSS N3-PEG2000-OPSS		Azide
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193H

Azide-PEG10000-OPSS N3-PEG10000-OPSS		Azide
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193B

Azide-PEG1000-OPSS N3-PEG1000-OPSS		Azide
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193D

Azide-PEG3400-OPSS N3-PEG3400-OPSS		Azide
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193A

Azide-PEG600-OPSS N3-PEG600-OPSS		Azide
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-179193

Azide-PEG400-OPSS N3-PEG400-OPSS		Azide
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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acetylenic compound

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