1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Lenalidomide-acetylene-C5-COOH

Lenalidomide-acetylene-C5-COOH (Synonyms: Cereblon ligand-linker Conjugate)

Cat. No.: HY-129608
Handling Instructions

Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC.

For research use only. We do not sell to patients.

Lenalidomide-acetylene-C5-COOH Chemical Structure

Lenalidomide-acetylene-C5-COOH Chemical Structure

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Description

Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1].

IC50 & Target[1]

Cereblon

 

Molecular Weight

382.41

Formula

C₂₁H₂₂N₂O₅

SMILES

O=C1N(C2C(NC(CC2)=O)=O)CC3=C1C=CC=C3C#CCCCCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Lenalidomide-acetylene-C5-COOHCereblon ligand-linker ConjugateE3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Product name:
Lenalidomide-acetylene-C5-COOH
Cat. No.:
HY-129608
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