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Results for "

atherogenic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Apoptosis (1) Aryl Hydrocarbon Receptor (1) Bacterial (3) Cytochrome P450 (1) Endogenous Metabolite (4) Fungal (3) Isotope-Labeled Compounds (1) PARP (1) PDGFR (1) PPAR (2) Reactive Oxygen Species (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (3) Infection (3) Inflammation/Immunology (9) Metabolic Disease (5) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113162

Bovinic acid

Endogenous Metabolite Metabolic Disease

Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

Bovinic acid	Endogenous Metabolite	Metabolic Disease
Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-N4137

Tormentic acid	Others	Cardiovascular Disease Inflammation/Immunology
Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .

HY-N0570

Hydroxytyrosol 5 Publications Verification DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol	Endogenous Metabolite Bacterial Fungal	Infection Inflammation/Immunology Cancer
Hydroxytyrosol (DOPET) is a phenolic compound with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects .

HY-153497

Vupanorsen IONIS ANGPT-L3Rx; ISIS 703802	Others	Metabolic Disease
Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.

HY-153497A

Vupanorsen sodium IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium	Others	Metabolic Disease
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.

HY-121542

PPARδ agonist 10	PPAR	Metabolic Disease
PPARδ agonist 10 (compound 7) is an orally active, selective, and partial agonist of PPARδ, with EC₅₀ values of 0.053 μM and 0.30 µM for hPPARδ(LBD)-GAL4 and mPPARδ, respectively. PPARδ agonist 10 is a partial PPARδ agonist in transactivation assay but a full agonist on free fatty acids (FFA) oxidation in muscle cells both in vitro and in vivo. PPARδ agonist 10 can be used for dyslipidemia research .

HY-N0570S1

Hydroxytyrosol-d5 DOPET-d₅; 3,4-Dihydroxyphenethyl alcohol-d₅; 3-Hydroxytyrosol-d₅	Endogenous Metabolite Bacterial Fungal	Infection Inflammation/Immunology Cancer
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-N0570S

Hydroxytyrosol-d4 DOPET-d₄; 3,4-Dihydroxyphenethyl alcohol-d₄; 3-Hydroxytyrosol-d₄	Isotope-Labeled Compounds Endogenous Metabolite Bacterial Fungal	Infection Inflammation/Immunology Cancer
Hydroxytyrosol-d₄ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-N0292

Oleuropein 1 Publications Verification	Cytochrome P450 PPAR Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase .

HY-129440

N-(p-Coumaroyl) Serotonin	PDGFR	Metabolic Disease Inflammation/Immunology
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca ²⁺ release from sarcoplasmic reticulum . N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research .

HY-P5169

LVGRQLEEFL (mouse)	Amino Acid Derivatives	Inflammation/Immunology
LVGRQLEEFL (mouse) can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ)}. LVGRQLEEFL (mouse) exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death .

HY-P5169A

LVGRQLEEFL (mouse) (TFA)	Amino Acid Derivatives	Inflammation/Immunology
LVGRQLEEFL (mouse) TFA can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ)}. LVGRQLEEFL (mouse) TFA exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) TFA can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death .

HY-N8572

3',4'-Dimethoxyflavone	PARP Reactive Oxygen Species Aryl Hydrocarbon Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
3',4'-Dimethoxyflavone is a lipophilic flavone, can be isolated from the leaves of Primula veris. 3',4'-Dimethoxyflavone can reduce the synthesis and accumulation of PARP and protect cortical neurones against cell death induced by Parthanatos. 3',4'-Dimethoxyflavone is also an aryl hydrocarbon receptor antagonist in human breast cancer cells. 3',4'-Dimethoxyflavone can promote the proliferation of human hematopoietic stem cells. 3',4'-Dimethoxyflavone has various biological activities, including antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidaemic, and neuroprotective or neurotrophic effects .

LVGRQLEEFL (mouse)	Amino Acid Derivatives	Inflammation/Immunology
LVGRQLEEFL (mouse) can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ)}. LVGRQLEEFL (mouse) exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death .

LVGRQLEEFL (mouse) (TFA)	Amino Acid Derivatives	Inflammation/Immunology
LVGRQLEEFL (mouse) TFA can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ)}. LVGRQLEEFL (mouse) TFA exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) TFA can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113162

Bovinic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-N4137

Tormentic acid	Cardiovascular Disease Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Rosaceae Plants Disease Research Fields Rosa rugosa Thunb.	Others
Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .

HY-N0570

Hydroxytyrosol 5 Publications Verification DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol	Infection Classification of Application Fields Canarium album (Lour.) Rauesch. Source classification Phenols Polyphenols Plants Burseraceae Endogenous metabolite Disease Research Fields Inflammation/Immunology	Endogenous Metabolite Bacterial Fungal
Hydroxytyrosol (DOPET) is a phenolic compound with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects .

HY-N0292

Oleuropein 1 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Anti-aging Source classification Plants Burseraceae Iridoids Canarium album (Lour.) Rauesch. Terpenoids Phenols Polyphenols Inflammation/Immunology Disease Research Fields Cancer	Cytochrome P450 PPAR Apoptosis
Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase .

HY-129440

N-(p-Coumaroyl) Serotonin	Classification of Application Fields Carthamus tinctorius L. Source classification Phenols Polyphenols Plants Compositae Disease Research Fields Inflammation/Immunology	PDGFR
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca ²⁺ release from sarcoplasmic reticulum . N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research .

HY-N8572

3',4'-Dimethoxyflavone	Flavonoids other families Flavones Coniogramme japonica (Thunb.) Diels Plants	PARP Reactive Oxygen Species Aryl Hydrocarbon Receptor
3',4'-Dimethoxyflavone is a lipophilic flavone, can be isolated from the leaves of Primula veris. 3',4'-Dimethoxyflavone can reduce the synthesis and accumulation of PARP and protect cortical neurones against cell death induced by Parthanatos. 3',4'-Dimethoxyflavone is also an aryl hydrocarbon receptor antagonist in human breast cancer cells. 3',4'-Dimethoxyflavone can promote the proliferation of human hematopoietic stem cells. 3',4'-Dimethoxyflavone has various biological activities, including antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidaemic, and neuroprotective or neurotrophic effects .

Cat. No.	Product Name	Chemical Structure

HY-N0570S

Hydroxytyrosol-d4
Hydroxytyrosol-d₄ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-N0570S1

Hydroxytyrosol-d5
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

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atherogenic

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products