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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
carnitine palmitoyltransferase-I
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "carnitine palmitoyltransferase-I" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: (-)-Lauroylcarnitine
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-U00159
CAS No.: 69207-52-9
Synonyms: Methyl palmoxirate; NSC359682
Research Areas:
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.
Cat. No.: HY-B2004
CAS No.: 130000-40-7
Research Areas:
Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Cat. No.: HY-172548
Research Areas:
Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
Cat. No.: HY-W104819
CAS No.: 15573-67-8
Synonyms: 4-Hydroxyphenylglyoxylic acid; 4-HPGA
Research Areas:
4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of carnitine palmitoyltransferase I (CPT I). 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation .
Cat. No.: HY-B2004R
CAS No.: 130000-40-7
Research Areas:
Thifluzamide (Standard) is the analytical standard of Thifluzamide. This product is intended for research and analytical applications. Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Cat. No.: HY-113166R
CAS No.: 25518-54-1
Synonyms: (-)-Lauroylcarnitine (Standard)
Cat. No.: HY-P86822
Synonyms: carnitine O palmitoyltransferase 1 liver isoform antibody; carnitine O palmitoyltransferase I antibody; carnitine O palmitoyltransferase I liver isoform antibody; carnitine O-palmitoyltransferase 1 antibody; carnitine O-palmitoyltransferase I antibody; carnitine palmitoyltransferase 1A (liver) antibody; carnitine palmitoyltransferase 1A antibody; carnitine palmitoyltransferase I antibody; carnitine palmitoyltransferase I liver antibody; CPT 1 antibody; carnitine O palmitoyltransferase 1 liver isoform antibody; carnitine O palmitoyltransferase I antibody; carnitine O palmitoyltransferase I liver isoform antibody; carnitine O-palmitoyltransferase 1 antibody; carnitine O-palmitoyltransferase I antibody; carnitine palmitoyltransferase 1A (liver) antibody; carnitine palmitoyltransferase 1A antibody; carnitine palmitoyltransferase I antibody; carnitine palmitoyltransferase I liver antibody; CPT 1 antibody; CPT I antibody; CPT1 antibody; CPT1 L antibody; CPT1-L antibody; Cpt1a antibody; CPT1A_HUMAN antibody; CPTI antibody; CPTI-L antibody; L CPT1 antibody; liver isoform antibody;
Cat. No.: HY-176894
CAS No.: 141661-39-4
Research Areas:
Hemiacetylcarnitinium chloride is a inhibitor of fatty acid metabolism, specifically targeting carnitine palmitoyltransferase I (CPT I). Hemiacetylcarnitinium chloride disrupts the conversion of fatty acyl-CoA to fatty acyl carnitine, thereby blocking the subsequent oxidation of long-chain fatty acids and reducing the production of ATP required for energy-dependent cellular processes. Hemiacetylcarnitinium chloride can be used for the study of fatty acid metabolism .
Cat. No.: HY-182248
CAS No.: 908566-80-3
Synonyms: ST1326 chloride
Research Areas:
Teglicar chloride (ST1326 chloride) is an orally active, reversible, mixed-type, selective inhibitor of hepatic carnitine palmitoyltransferase I (L-CPT I), with an IC50 of 1.1 μM against rat L-CPT I. Teglicar chloride reduces serum glucose levels. Teglicar chloride exhibits antiketotic activity in normal fasted rats. Teglicar chloride can be used in research related to type 2 diabetes and ketoacidosis .
Cat. No.: HY-P77078
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CPT1B; carnitine O-palmitoyltransferase 1B; carnitine palmitoyltransferase 1B; CPTI-M; CPT1-M; KIAA1670; carnitine O-palmitoyltransferase 1, Muscle Isoform; MCCPT1; M-CPT1; CPT1M; carnitine O-palmitoyltransferase I, Muscle Isoform; MCPT1; carnitine Palmit
Species:
Mouse
Source:
HEK293
Cat. No.: HY-W563489
CAS No.: 88431-47-4
Synonyms: POCA
Research Areas:
Clomoxir (POCA) is a carnitine palmitoyltransferase I (CPT I) inhibitor with hypoglycemic activity. Clomoxir mediates the inhibition of CPT I via its active form POCA-CoA. Clomoxir inhibits long-chain fatty acid oxidation, ketogenesis, gluconeogenesis, de novo synthesis of cholesterol and fatty acids, and also mildly inhibits acetyl-CoA carboxylase. Clomoxir reduces blood glucose levels in various rodent and porcine models, alters plasma NEFA and cholesterol concentrations, induces hepatic lipid accumulation, peroxisome proliferation and mild myocardial hypertrophy in rats, and stimulates the pentose phosphate pathway in cultured human fibroblasts. Clomoxir can be used in diabetes-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
