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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

drug coupling

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

1

Screening Libraries

25

Biochemical Assay Reagents

1

Peptides

1

Inhibitory Antibodies

3

Click Chemistry

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011556
    N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate

    TCFH

    		 Drug Isomer Cancer
    N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a powerful coupling and derivatizing reagent for ester prodrug synthesis. N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate can be used for antitumor drugs before medicine research .
    N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate
  • HY-114362
    DL-alpha-Tocopherol methoxypolyethylene glycol succinate

    TPGS-750-M

    		 Biochemical Assay Reagents Others
    DL-alpha-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M) is an amphiphile, acts as a surfactant. DL-alpha-Tocopherol methoxypolyethylene glycol succinate has a positive effect on Suzuki-Miyaura cross coupling. DL-alpha-Tocopherol methoxypolyethylene glycol succinate increases the styrene titer. DL-alpha-Tocopherol methoxypolyethylene glycol succinate is used in the stability test of NPYM-modified drugs in biological fluids .
    DL-alpha-Tocopherol methoxypolyethylene glycol succinate
  • HY-147363
    DIBAC-GGFG-NH2CH2-Dxd

    		Drug-Linker Conjugates for ADC Others
    DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates . Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DIBAC-GGFG-NH2CH2-Dxd
  • HY-W090940
    H-Gly-Gly-Phe-OH

    		ADC Linker Cancer
    H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
    H-Gly-Gly-Phe-OH
  • HY-101532
    6A-Azido-6A-deoxy-β-cyclodextrin

    β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin

    		 Biochemical Assay Reagents Others
    6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3) is a site-specifically modified β-cyclodextrin with a single azido group replacing the hydroxyl group at the C6 position. 6A-Azido-6A-deoxy-β-cyclodextrin forms a host-guest inclusion complex with Dexamethasone (HY-14648), localizing the drug within its hydrophobic cavity, which restricts the rotational mobility of the drug and places Dexamethasone in a less polar environment. 6A-Azido-6A-deoxy-β-cyclodextrin acts as a coupling agent to graft β-cyclodextrin onto thermosensitive nanogels via strain-promoted alkyne-azide cycloaddition (SPAAC). 6A-Azido-6A-deoxy-β-cyclodextrin also serves as a click chemistry reagent. It contains an azide group and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules bearing an alkyne group. It also undergoes strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
    6A-Azido-6A-deoxy-β-cyclodextrin
  • HY-151721
    H-D-Orn(N3)-OH hydrochloride

    		Drug Intermediate Others
    H-D-Orn(N3)-OH hydrochloride is a drug intermediate that can be introduced at the 5' end of oligonucleotides with a protected C6 amino linker by MMT, facilitating the subsequent deprotection and coupling of functional groups such as dyes and biotin.
    H-D-Orn(N3)-OH hydrochloride
  • HY-W004650A
    TETA tetraTFA

    		Biochemical Assay Reagents Others
    TETA (tetraTFA) is an effective selective chelating agent for copper (II). TETA (tetraTFA) can be used for drug coupling .
    TETA tetraTFA
  • HY-171987
    trans-4-Hydroxyprolinol-C10-tri-GalNAc

    		Drug Derivative Others
    trans-4-Hydroxyprolinol-C10-tri-GalNAc (Formula XXIV) is a Tri-GaINAc derivative that can be used for nucleic acid drug coupling .
    trans-4-Hydroxyprolinol-C10-tri-GalNAc
  • HY-W004698
    (2-Methoxypyrimidin-5-yl)boronic acid

    		Drug Intermediate Others
    (2-Methoxypyrimidin-5-yl)boronic acid is a drug intermediate that can serve as a key reactant in the Suzuki-Miyaura coupling reaction, and is used for the synthesis of isoquinoline ketone derivatives with anti-tumor activity .
    (2-Methoxypyrimidin-5-yl)boronic acid
  • HY-P4565
    Phe-Arg-Arg-Gly

    		Cathepsin Others
    Phe-Arg-Arg-Gly is a polypeptide that can be used for agent coupling .
    Phe-Arg-Arg-Gly
  • HY-158709
    Cho-es-Lys

    		Biochemical Assay Reagents Liposome Others
    Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .
    Cho-es-Lys
  • HY-174896A
    DSPE-PEG2000-Fmoc

    		Biochemical Assay Reagents Others
    DSPE-PEG2000-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
    DSPE-PEG2000-Fmoc
  • HY-W800625
    Boc-PEG4-Val-Cit-PAB-OH

    		ADC Linker Cancer
    Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
    Boc-PEG4-Val-Cit-PAB-OH
  • HY-W800621
    Fmoc-PEG2-Val-Cit-PAB-OH

    		ADC Linker Cancer
    Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine for use in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
    Fmoc-PEG2-Val-Cit-PAB-OH
  • HY-W800623
    Fmoc-PEG6-Val-Cit-PAB-OH

    		ADC Linker Cancer
    Fmoc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
    Fmoc-PEG6-Val-Cit-PAB-OH
  • HY-W800624
    Boc-PEG2-Val-Cit-PAB-OH

    		ADC Linker Cancer
    Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
    Boc-PEG2-Val-Cit-PAB-OH
  • HY-W800622
    Fmoc-PEG4-Val-Cit-PAB-OH

    		ADC Linker Cancer
    Fmoc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
    Fmoc-PEG4-Val-Cit-PAB-OH
  • HY-W800618
    NH2-PEG3-Val-Cit-PAB-OH

    		ADC Linker Others
    NH2-PEG3-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
    NH2-PEG3-Val-Cit-PAB-OH
  • HY-W800617
    NH2-PEG1-Val-Cit-PAB-OH

    		ADC Linker Cancer
    NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
    NH2-PEG1-Val-Cit-PAB-OH
  • HY-W800619
    NH2-PEG4-Val-Cit-PAB-OH

    		ADC Linker Others
    NH2-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
    NH2-PEG4-Val-Cit-PAB-OH
  • HY-W800620
    NH2-PEG6-Val-Cit-PAB-OH

    		ADC Linker Others
    NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
    NH2-PEG6-Val-Cit-PAB-OH
  • HY-180563
    ADC 38 drug linker

    		Drug-Linker Conjugates for ADC Infection
    ADC 38 drug linker is a drug linker coupling agent used for ADCs, consisting of a CD4 mimic and a linker. ADC 38 drug linker can be used to synthesize antibody-drug conjugates (ADCs), such as ADC 38 .
    ADC 38 drug linker
  • HY-174896
    DSPE-PEG1000-Fmoc

    		Biochemical Assay Reagents Others
    DSPE-PEG1000-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
    DSPE-PEG1000-Fmoc
  • HY-174896B
    DSPE-PEG3400-Fmoc

    		Biochemical Assay Reagents Others
    DSPE-PEG3400-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
    DSPE-PEG3400-Fmoc
  • HY-174896C
    DSPE-PEG5000-Fmoc

    		Biochemical Assay Reagents Others
    DSPE-PEG5000-Fmoc is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed when a specific coupling reaction is required.
    DSPE-PEG5000-Fmoc
  • HY-183159B
    DSG-PEG3400-Glucose

    		Biochemical Assay Reagents Others
    DSG-PEG3400-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSG-PEG3400-Glucose
  • HY-183159C
    DSG-PEG5000-Glucose

    		Biochemical Assay Reagents Others
    DSG-PEG5000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG5000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSG-PEG5000-Glucose
  • HY-183159
    DSG-PEG1000-Glucose

    		Biochemical Assay Reagents Others
    DSG-PEG1000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG1000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSG-PEG1000-Glucose
  • HY-W1052981A
    DSPE-PEG5000-Glucose

    		Biochemical Assay Reagents Others
    DSPE-PEG5000-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG5000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSPE-PEG5000-Glucose
  • HY-W1052981D
    DSPE-PEG3400-Glucose

    		Biochemical Assay Reagents Others
    DSPE-PEG3400-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSPE-PEG3400-Glucose
  • HY-W1052981B
    DSPE-PEG10000-Glucose

    		Biochemical Assay Reagents Others
    DSPE-PEG10000-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG10000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSPE-PEG10000-Glucose
  • HY-183159D
    DSG-PEG10000-Glucose

    		Biochemical Assay Reagents Others
    DSG-PEG10000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG10000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSG-PEG10000-Glucose
  • HY-W1052981E
    DSPE-PEG1000-Glucose

    		Biochemical Assay Reagents Others
    DSPE-PEG1000-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG1000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSPE-PEG1000-Glucose
  • HY-W1052981
    DSPE-PEG2000-Glucose

    		Biochemical Assay Reagents Others
    DSPE-PEG2000-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSPE-PEG2000-Glucose
  • HY-183159A
    DSG-PEG2000-Glucose

    		Biochemical Assay Reagents Others
    DSG-PEG2000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DSG-PEG2000-Glucose
  • HY-183156D
    DMG-PEG10000-Glucose

    		Biochemical Assay Reagents Others
    DMG-PEG10000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG10000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DMG-PEG10000-Glucose
  • HY-183156A
    DMG-PEG2000-Glucose

    		Biochemical Assay Reagents Others
    DMG-PEG2000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DMG-PEG2000-Glucose
  • HY-183156
    DMG-PEG1000-Glucose

    		Biochemical Assay Reagents Others
    DMG-PEG1000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG1000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DMG-PEG1000-Glucose
  • HY-183156B
    DMG-PEG3400-Glucose

    		Biochemical Assay Reagents Others
    DMG-PEG3400-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DMG-PEG3400-Glucose
  • HY-183156C
    DMG-PEG5000-Glucose

    		Biochemical Assay Reagents Others
    DMG-PEG5000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG5000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    DMG-PEG5000-Glucose
  • HY-183169B
    C18-PEG5000-NHS

    		Biochemical Assay Reagents Others
    C18-PEG5000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG5000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    C18-PEG5000-NHS
  • HY-183169
    C18-PEG2000-NHS

    		Biochemical Assay Reagents Others
    C18-PEG2000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG2000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    C18-PEG2000-NHS
  • HY-183169A
    C18-PEG3400-NHS

    		Biochemical Assay Reagents Others
    C18-PEG3400-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG3400-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
    C18-PEG3400-NHS
  • HY-P991906
    TRPH-222 Antibody

    CD22-4AP Antibody; CAT-02-106 Antibody

    		 ADC Antibody CD22 Cancer
    TRPH-222 Antibody (CD22-4AP Antibody) is an anti-human CD22 antibody site-specifically modified at one site per heavy chain to express formylglycine (FG), allowing site-specific conjugation of a maytansinoid payload, a protease-insensitive spacer, and a functional group for coupling to an aldehyde on antibody FG residues. TRPH-222 Antibody can generate antibody drug conjugate (ADC) (TRPH-222) with an ADC payload and a linker. TRPH-222 Antibody can be used for the study of NHL (non-Hodgkin's lymphoma) .
    TRPH-222 Antibody

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