extension

By Targets:	Bacterial (4) Biochemical Assay Reagents (1) Cryptochrome (1) DNA/RNA Synthesis (1) Endogenous Metabolite (1) HCV (1) Microtubule/Tubulin (2) Reactive Oxygen Species (1) SARS-CoV (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (5) Metabolic Disease (1) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0162

Quinupristin 1 Publications Verification
Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .

HY-13247

Setrobuvir ANA598	DNA/RNA Synthesis HCV SARS-CoV	Infection
Setrobuvir (ANA598) is an orally active non-nucleosidic HCV NS5B polymerase inhibitor. ANA-598 inhibits both de novo RNA synthesis and primer extension, with IC₅₀s between 4 and 5 nM. Setrobuvir also shows excellent binding affinity to SARS-CoV-2 RdRp and induces RdRp inhibition .

HY-137911

Sparsomycin	Bacterial	Infection Cancer
Sparsomycin is a metabolite of the bacterium Streptomyces sparsogenes. Sparsomycin inhibits protein synthesis in both eukaryotic cells and bacteria. Sparsomycin inhibits the translation extension of ribosome PTC .

HY-A0162A

Quinupristin mesylate	Bacterial	Infection
Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .

HY-155869A

5-fluoro-dCTP sodium 5-Fluoro-2′-deoxycytidine 5′-triphosphate sodium	Others	Others
5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .

HY-155869

5-fluoro-dCTP 5-Fluoro-2′-deoxycytidine 5′-triphosphate	Others	Others
5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .

HY-119506

KL044	Cryptochrome	Metabolic Disease
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC₅₀ value of 7.32, leading to the extension of the circadian period and repression of Per2 activity .

HY-N8804

Shatavarin IV Asparanin B	Reactive Oxygen Species	Neurological Disease Cancer
Shatavarin IV is a steroidal saponin, that can be isolated from the roots of Asparagus racemosus (Liliaceae). Shatavarin IV shows anticancer activity. Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans .

HY-P5637

Tur1A	Bacterial	Infection
Tur1A is an antimicrobial peptide derived from bottlenose dolphins Tursiops truncates. Tur1A inhibits bacterial protein synthesis by binding to ribosomes and blocking the transition from the initiation stage to the extension stage .

HY-18407

N-Methylisatoic anhydride NMIA	Others	Others
N-Methylisatoic anhydride (NMIA) is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology .

HY-107116

MAP4343	Microtubule/Tubulin	Neurological Disease
MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents .

HY-147835

Antibacterial agent 109	Bacterial	Infection
Antibacterial agent 109 (Compound C-2) is a potent antibacterial agent against both gram-positive and gram negative bacteria, and non-mutagenic. Antibacterial agent 109 inhibits protein synthesis by blocking the extension of new peptide chains .

HY-D0199

Adenosine 5'-diphosphate disodium	Endogenous Metabolite	Cardiovascular Disease
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-107116S

MAP4343-d4	Microtubule/Tubulin
MAP4343-d₄ is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2][3].

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Cat. No.	Product Name	Type

HY-D0199

Adenosine 5'-diphosphate disodium	Biochemical Assay Reagents
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

all-cis-4,7,10,13,16-Docosapentaenoic acid

all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid

Biochemical Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Cat. No.	Product Name	Target	Research Area

HY-A0162A

Quinupristin mesylate	Bacterial	Infection
Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .

HY-P5637

Tur1A	Bacterial	Infection
Tur1A is an antimicrobial peptide derived from bottlenose dolphins Tursiops truncates. Tur1A inhibits bacterial protein synthesis by binding to ribosomes and blocking the transition from the initiation stage to the extension stage .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0199

Adenosine 5'-diphosphate disodium	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-N8804

Shatavarin IV Asparanin B	Structural Classification Natural Products Source classification Plants Asparagaceae Juss.	Reactive Oxygen Species
Shatavarin IV is a steroidal saponin, that can be isolated from the roots of Asparagus racemosus (Liliaceae). Shatavarin IV shows anticancer activity. Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans .

Cat. No.	Compare	Product Name	Species	Source

HY-P73806

	Moesin Protein, Human (His) Moesin; Membrane-organizing extension spike protein; MSN	Human	E. coli
	Moesin proteins connect the actin cytoskeleton to the plasma membrane and regulate cell cortical structure and function. Moesin Protein, Human (His) is the recombinant human-derived Moesin protein, expressed by E. coli , with N-His labeled tag. The total length of Moesin Protein, Human (His) is 346 a.a., with molecular weight of ~45 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-107116S

MAP4343-d4
MAP4343-d₄ is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2][3].

Cat. No.	Product Name	Application	Reactivity

HY-P82869

Phospho-Moesin (Thr558) Antibody (YA2614)

MSN; Moesin; Membrane-organizing extension spike protein; RDX; Radixin; EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
WB, IHC-P Human, Rat

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