1. Quinupristin

Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .

For research use only. We do not sell to patients.

Quinupristin Chemical Structure

Quinupristin Chemical Structure

CAS No. : 120138-50-3

Size Price Stock Quantity
1 mg USD 75 In-stock
5 mg USD 220 In-stock
10 mg USD 330 In-stock
25 mg USD 610 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Quinupristin:

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1 Publications Citing Use of MCE Quinupristin

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  • Purity & Documentation

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Description

Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].

In Vitro

Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections. Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp.[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1022.22

Formula

C53H67N9O10S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@](N(C([C@@](CCC1)([H])N1C([C@H](NC2=O)CC)=O)=O)C)([H])CC3=CC=C(N(C)C)C=C3)N(C[C@@H](CS[C@H]4C(CC5)CCN5C4)C6=O)[C@](C6)([H])C(N[C@@H](C7=CC=CC=C7)C(O[C@@H]([C@@H]2NC(C(N=CC=C8)=C8O)=O)C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (122.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9783 mL 4.8913 mL 9.7826 mL
5 mM 0.1957 mL 0.9783 mL 1.9565 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9783 mL 4.8913 mL 9.7826 mL 24.4566 mL
5 mM 0.1957 mL 0.9783 mL 1.9565 mL 4.8913 mL
10 mM 0.0978 mL 0.4891 mL 0.9783 mL 2.4457 mL
15 mM 0.0652 mL 0.3261 mL 0.6522 mL 1.6304 mL
20 mM 0.0489 mL 0.2446 mL 0.4891 mL 1.2228 mL
25 mM 0.0391 mL 0.1957 mL 0.3913 mL 0.9783 mL
30 mM 0.0326 mL 0.1630 mL 0.3261 mL 0.8152 mL
40 mM 0.0245 mL 0.1223 mL 0.2446 mL 0.6114 mL
50 mM 0.0196 mL 0.0978 mL 0.1957 mL 0.4891 mL
60 mM 0.0163 mL 0.0815 mL 0.1630 mL 0.4076 mL
80 mM 0.0122 mL 0.0611 mL 0.1223 mL 0.3057 mL
100 mM 0.0098 mL 0.0489 mL 0.0978 mL 0.2446 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Quinupristin
Cat. No.:
HY-A0162
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