Quinupristin
Based on 1 publication(s) in Google Scholar
Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits .
For research use only. We do not sell to patients.
- Purity: 98.71%
- CAS No.: 120138-50-3
- Formula: C53H67N9O10S
- Molecular Weight:1022.22
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Quinupristin
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Biological Activity
Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections.
Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp.[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 120138-50-3
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Appearance Solid
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Molecular Weight 1022.22
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Formula C53H67N9O10S
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Color White to off-white
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Sequence Shortening
T-Abu-PF-Pip-Phg (Lactone:Thr1-Phg6)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 125 mg/mL (122.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6. [Content Brief]
[2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3). [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9783 mL | 4.8913 mL | 9.7826 mL | 24.4566 mL |
| 5 mM | 0.1957 mL | 0.9783 mL | 1.9565 mL | 4.8913 mL | |
| 10 mM | 0.0978 mL | 0.4891 mL | 0.9783 mL | 2.4457 mL | |
| 15 mM | 0.0652 mL | 0.3261 mL | 0.6522 mL | 1.6304 mL | |
| 20 mM | 0.0489 mL | 0.2446 mL | 0.4891 mL | 1.2228 mL | |
| 25 mM | 0.0391 mL | 0.1957 mL | 0.3913 mL | 0.9783 mL | |
| 30 mM | 0.0326 mL | 0.1630 mL | 0.3261 mL | 0.8152 mL | |
| 40 mM | 0.0245 mL | 0.1223 mL | 0.2446 mL | 0.6114 mL | |
| 50 mM | 0.0196 mL | 0.0978 mL | 0.1957 mL | 0.4891 mL | |
| 60 mM | 0.0163 mL | 0.0815 mL | 0.1630 mL | 0.4076 mL | |
| 80 mM | 0.0122 mL | 0.0611 mL | 0.1223 mL | 0.3057 mL | |
| 100 mM | 0.0098 mL | 0.0489 mL | 0.0978 mL | 0.2446 mL |
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