120138-50-3
Chemical Structure
Quinupristin
- CAS No.: 120138-50-3
- Formula:C53H67N9O10S
- Molecular Weight:1022.22
IUPAC Name: N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(4-(dimethylamino)benzyl)-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-((((S)-quinuclidin-3-yl)thio)methyl)docosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1]oxa[4,7,10,13,16]pentaazacyclononadecin-9-y
InChIKey: WTHRRGMBUAHGNI-LCYNINFDSA-N
SMILES: O=C([C@](N(C([C@@](CCC1)([H])N1C([C@H](NC2=O)CC)=O)=O)C)([H])CC3=CC=C(N(C)C)C=C3)N(C[C@@H](CS[C@H]4C(CC5)CCN5C4)C6=O)[C@](C6)([H])C(N[C@@H](C7=CC=CC=C7)C(O[C@@H]([C@@H]2NC(C(N=CC=C8)=C8O)=O)C)=O)=O
Biological Activity: Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Quinupristin | 98.71% | Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits . | ||||||||||||||||||||
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Quinupristin (Standard) | ≥98% | Bictegravir (sodium) (Standard) is the analytical standard of Bictegravir (sodium). This product is intended for research and analytical applications. Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity. | ||||||||||||||||||||
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References
- [1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6. [Content Brief]
- [2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3). [Content Brief]
