1. Others
  2. Others
  3. KL044

KL044 

Cat. No.: HY-119506
Handling Instructions

KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.

For research use only. We do not sell to patients.

KL044 Chemical Structure

KL044 Chemical Structure

CAS No. : 1801856-93-8

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity[1].

IC50 & Target

pEC50: 7.32[1]

In Vitro

KL044 (0-3.7 μM; 8 h) effectively stabilizes the CRY1-LUC fusion protein without affecting the stability of LUC in the HEK293 stable cell line[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

359.81

Formula

C₂₁H₁₄ClN₃O

CAS No.

1801856-93-8

SMILES

O=C(CN1C2=C(C=CC=C2)C3=C1C=CC=C3)NC4=C(C=CC=C4Cl)C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

KL044KL 044KL-044OthersprobecircadiansyntheticInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
KL044
Cat. No.:
HY-119506
Quantity:
MCE Japan Authorized Agent: