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Results for "

hydrogen peroxide-induced oxidative stress

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Fluorescent Dyes

2

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-172942
    SP11

    		Mitochondrial Metabolism Reactive Oxygen Species (ROS) Dynamin Cardiovascular Disease Infection Neurological Disease Cancer
    SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinson’s disease .
    SP11
  • HY-B1608
    Chromium chloride

    		Cardiovascular Disease Metabolic Disease
    Chromium chloride is a trivalent chromium compound and an essential trace mineral. Chromium chloride enhances insulin-stimulated GLUT4 translocation and glucose uptake in skeletal muscle. Chromium chloride regulates glucose and lipid metabolism, inhibits TNF-α secretion and oxidative stress in monocytes treated with high glucose or H2O2, and reverses hydrogen peroxide-induced cell growth inhibition. Chromium chloride reduces coronary and aortic lipid deposition and serum cholesterol levels in hypercholesterolemic rabbits. Chromium chloride can be used in research related to diabetes and cardiac atherosclerosis .
    Chromium chloride
  • HY-D0830
    Calcein (tetraethyl ester)

    Fluorexon tetraethyl ester

    		 Fluorescent Dye Others
    Calcein tetraethyl ester is a tetraethylated derivative of calcein, with its core function serving as a live cell-specific fluorescent tracer. Calcein tetraethyl ester can diffuse between human periodontal ligament cells via gap junctions, thus enabling the evaluation of gap junction intercellular communication function, and its diffusion is enhanced under hydrogen peroxide induction. Calcein tetraethyl ester can be applied in the fields of cell biology and fluorescent labeling .
    Calcein (tetraethyl ester)
  • HY-N17872
    Tenuifoliose W

    		Drug Derivative Inflammation/Immunology
    Tenuifoliose W is a sugar ester found in the roots of Polygala tenuifolia Willd. Tenuifoliose W targets hydrogen peroxide-induced oxidative stress in keratinocytes. Tenuifoliose W can be used for the research of skin aging .
    Tenuifoliose W
  • HY-179711
    AChE/BChE-IN-32

    		Cholinesterase (ChE) Amyloid-β Neurological Disease
    AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 μM respectively. AChE/BChE-IN-32 inhibits Aβ aggregation and exhibits a strong ABTS•+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimer's disease .
    AChE/BChE-IN-32
  • HY-P11638
    Mitochondrial-targeted peptide BP29

    		Mitochondrial Metabolism Neurological Disease Inflammation/Immunology
    Mitochondrial-targeted peptide BP29 is a mitochondria-targeted iron chelator linked to a mitochondria-homing SS-peptide. Mitochondrial-targeted peptide BP29 protects human primary skin fibroblasts against ultraviolet A-induced oxidative damage to mitochondrial membranes, ATP depletion, and necrotic cell death. Mitochondrial-targeted peptide BP29 prevents hydrogen peroxide-induced oxidative stress and cytotoxicity in both healthy and Friedreich's ataxia skin fibroblasts. Mitochondrial-targeted peptide BP29 can be used for the research of Friedreich's ataxia .
    Mitochondrial-targeted peptide BP29
  • HY-P11638A
    Mitochondrial-targeted peptide BP29 acetate

    		Mitochondrial Metabolism Neurological Disease Inflammation/Immunology
    Mitochondrial-targeted peptide BP29 acetate is a mitochondria-targeted iron chelator linked to a mitochondria-homing SS-peptide. Mitochondrial-targeted peptide BP29 acetate protects human primary skin fibroblasts against ultraviolet A-induced oxidative damage to mitochondrial membranes, ATP depletion, and necrotic cell death. Mitochondrial-targeted peptide BP29 acetate prevents hydrogen peroxide-induced oxidative stress and cytotoxicity in both healthy and Friedreich's ataxia skin fibroblasts. Mitochondrial-targeted peptide BP29 acetate can be used for the research of Friedreich's ataxia .
    Mitochondrial-targeted peptide BP29 acetate

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