2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. Mitochondrial-targeted peptide BP29 acetate

Mitochondrial-targeted peptide BP29 acetate 

Cat. No.: HY-P11638A Purity: 98.15%
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Mitochondrial-targeted peptide BP29 acetate is a mitochondria-targeted iron chelator linked to a mitochondria-homing SS-peptide. Mitochondrial-targeted peptide BP29 acetate protects human primary skin fibroblasts against ultraviolet A-induced oxidative damage to mitochondrial membranes, ATP depletion, and necrotic cell death. Mitochondrial-targeted peptide BP29 acetate prevents hydrogen peroxide-induced oxidative stress and cytotoxicity in both healthy and Friedreich's ataxia skin fibroblasts. Mitochondrial-targeted peptide BP29 acetate can be used for the research of Friedreich's ataxia.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Mitochondrial-targeted peptide BP29 acetate

Mitochondrial-targeted peptide BP29 acetate Chemical Structure

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Mitochondrial-targeted peptide BP29 acetate Related Antibodies

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Description

Mitochondrial-targeted peptide BP29 acetate is a mitochondria-targeted iron chelator linked to a mitochondria-homing SS-peptide. Mitochondrial-targeted peptide BP29 acetate protects human primary skin fibroblasts against ultraviolet A-induced oxidative damage to mitochondrial membranes, ATP depletion, and necrotic cell death. Mitochondrial-targeted peptide BP29 acetate prevents hydrogen peroxide-induced oxidative stress and cytotoxicity in both healthy and Friedreich's ataxia skin fibroblasts. Mitochondrial-targeted peptide BP29 acetate can be used for the research of Friedreich's ataxia[1].

In Vitro

Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FEK4 human primary skin fibroblasts against ultraviolet A (UVA)-induced oxidative damage and necrotic cell death[1].
Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FRDA skin fibroblasts against UVA-induced cell death[1].
Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FRDA and healthy skin fibroblasts against H2O2-induced cytotoxicity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mitochondrial-targeted peptide BP29 acetate Related Antibodies
Molecular Weight

1199.31 (free base)

Formula

C57H78N14O15·xC2H4O2
Appearance

Solid

Color

Light yellow to yellow

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
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Mitochondrial-targeted peptide BP29 acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mitochondrial-targeted peptide BP29Mitochondrial MetabolismInhibitorinhibitorinhibit

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