Mitochondrial-targeted peptide BP29 acetate
Based on 1 Customer Validation
Mitochondrial-targeted peptide BP29 acetate is a mitochondria-targeted iron chelator linked to a mitochondria-homing SS-peptide. Mitochondrial-targeted peptide BP29 acetate protects human primary skin fibroblasts against ultraviolet A-induced oxidative damage to mitochondrial membranes, ATP depletion, and necrotic cell death. Mitochondrial-targeted peptide BP29 acetate prevents hydrogen peroxide-induced oxidative stress and cytotoxicity in both healthy and Friedreich's ataxia skin fibroblasts. Mitochondrial-targeted peptide BP29 acetate can be used for the research of Friedreich's ataxia.
For research use only. We do not sell to patients.
- Purity: 98.15%
- Formula: C57H78N14O15·xC2H4O2
- Molecular Weight:1199.31 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FEK4 human primary skin fibroblasts against ultraviolet A (UVA)-induced oxidative damage and necrotic cell death[1].
Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FRDA skin fibroblasts against UVA-induced cell death[1].
Mitochondrial-targeted peptide BP29 (50 μM; overnight pre-treatment) acetate protects FRDA and healthy skin fibroblasts against H2O2-induced cytotoxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1199.31 (free base)
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Formula C57H78N14O15·xC2H4O2
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Color Light yellow to yellow
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mitochondrial-targeted peptide BP29 acetate Related Classifications
HY-P11638A Related Classifications
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