AChE/BChE-IN-32
AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 μM respectively. AChE/BChE-IN-32 inhibits Aβ aggregation and exhibits a strong ABTS•+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimer's disease.
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- Formel: C24H34N4O2
- Molecular Weight:410.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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AChE 2.48 μM (Ki) |
BChE 0.696 μM (Ki) |
Chemical Information
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Molecular Weight 410.55
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Formel C24H34N4O2
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SMILES
OC1=C(CNCCCCNC2=C(CCC3)C3=NC4=C2CCCC4)C(CO)=CN=C1C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)