AChE/BChE-IN-32
AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 μM respectively. AChE/BChE-IN-32 inhibits Aβ aggregation and exhibits a strong ABTS•+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C24H34N4O2
- Molecular Weight:410.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE 2.48 μM (Ki) |
BChE 0.696 μM (Ki) |
Chemical Information
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Molecular Weight 410.55
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Formula C24H34N4O2
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SMILES
OC1=C(CNCCCCNC2=C(CCC3)C3=NC4=C2CCCC4)C(CO)=CN=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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