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Results for "

neutrophil elastase (NE)

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Peptides

1

Recombinant Proteins

3

Antibodies

Targets Recommended:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-15651
    Alvelestat
    10+ Cited Publications

    AZD9668

    		 Elastase Inflammation/Immunology
    Alvelestat (AZD9668) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC50 value of 7.9 nM, a Ki value of 9.4 nM and a Kd value of 9.5 nM .
    Alvelestat
  • HY-132132
    Neutrophil elastase inhibitor 3

    		Elastase Inflammation/Immunology
    Neutrophil elastase inhibitor 3 (compound 13), a benzoxazinone analog, shows effects on superoxide anion generation and exhibits as a neutrophil elastase (NE) inhibitor, with an IC50 of 80.8 nM for NE release .
    Neutrophil elastase inhibitor 3
  • HY-P2922
    Cathepsin C

    		Cathepsin Cancer
    Cathepsin C is a lysosomal cysteine protease essential for catalytic activation of many serine proteases, including proteinase 3 (PR3), neutrophil elastase (NE), cathepsin G (CTSG), granzyme A/B/C, and mast cell chymase .
    Cathepsin C
  • HY-U00256
    ZD8321

    		Elastase Inflammation/Immunology Cancer
    ZD8321 is a potent inhibitor of human Neutrophil elastase (NE) with a Ki of 13±1.7 nM.
    ZD8321
  • HY-15651A
    Alvelestat tosylate

    AZD9668 tosylate

    		 Elastase Inflammation/Immunology
    Alvelestat (tosylate) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC50 value of 7.9 nM, a Ki value of 9.4 nM and a Kd value of 9.5 nM .
    Alvelestat tosylate
  • HY-15651R
    Alvelestat (Standard)

    AZD9668 (Standard)

    		 Elastase Reference Standards Inflammation/Immunology
    Alvelestat (Standard) is the analytical standard of Alvelestat. This product is intended for research and analytical applications. Alvelestat (AZD9668) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC50 value of 7.9 nM, a Ki value of 9.4 nM and a Kd value of 9.5 nM .
    Alvelestat (Standard)
  • HY-P3648
    Ala-Ala-Pro-Val-chloromethylketone

    AAPV-CMK

    		 Elastase Inflammation/Immunology
    Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .
    Ala-Ala-Pro-Val-chloromethylketone
  • HY-11046A
    KRP-109

    		Endogenous Metabolite Inflammation/Immunology
    KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia .
    KRP-109
  • HY-11046
    AX-9657

    		Elastase Inflammation/Immunology
    KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia .
    AX-9657
  • HY-182465
    CHF-6333 chloride

    		Elastase Inflammation/Immunology
    CHF-6333 chloride is a neutrophil elastase (NE) inhibitor (IC50 = 0.21 nM; KD = 0.16 nM). CHF-6333 chloride retains its activity in both human (IC50 = 0.22 nM) and rat (IC50 = 3.63 nM) proteases. CHF-6333 chloride exhibits inhibitory activity against Proteinase 3 (IC50 = 22 nM). CHF-6333 chloride can be used for the study of bronchiectasis (BE) .
    CHF-6333 chloride
  • HY-179566
    CHF-6333

    		Elastase Inflammation/Immunology
    CHF-6333 is a neutrophil elastase (NE) inhibitor (IC50 = 0.21 nM; KD = 0.16 nM). CHF-6333 retains its activity in both human (IC50 = 0.22 nM) and rat (IC50 = 3.63 nM) proteases. CHF-6333 exhibits inhibitory activity against Proteinase 3 (IC50 = 22 nM). CHF-6333 can be used for the study of bronchiectasis (BE) .
    CHF-6333
  • HY-179566A
    CHF-6333 xinafoate

    		Elastase Inflammation/Immunology
    CHF-6333 xinafoate is a neutrophil elastase (NE) inhibitor (IC50 = 0.21 nM; KD = 0.16 nM). CHF6333 xinafoate retains its activity in both human (IC50 = 0.22 nM) and rat (IC50 = 3.63 nM) proteases. CHF6333 xinafoate exhibits inhibitory activity against Proteinase 3 (IC50 = 22 nM). CHF-6333 xinafoate can be used for the study of bronchiectasis (BE) .
    CHF-6333 xinafoate

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