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AX-9657

KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia.

For research use only. We do not sell to patients.

  • CAS No.: 1015439-77-6
  • Formula: C22H26N4O3
  • Molecular Weight:394.47
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AX-9657 Chemical Structure
    AX-9657 Chemical Structure
CAS No.: 1015439-77-6
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