photothermal

By Targets:	Apoptosis (3) Biochemical Assay Reagents (3) Environmental Pollutants (1) Fluorescent Dye (8) Liposome (1) Microtubule/Tubulin (1) PD-1/PD-L1 (1) Photosensitizer (1) Reactive Oxygen Species (ROS) (2)
By Research Areas:	Cancer (11) Inflammation/Immunology (1)
Click Chemistry:	DBCO (1)
Oligonucleotides:	Pegylated Lipids (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1063

IR-780 5+ Cited Publications	Fluorescent Dye Apoptosis Reactive Oxygen Species (ROS)	Cancer
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .

HY-164117

BNN6 1 Publications Verification	Reactive Oxygen Species (ROS) Apoptosis	Cancer
BNN6 is a thermoresponsive nitric oxide (NO) donor that often works by binding to a carrier. BNN6 decomposes under the heat stimulation generated by photothermal action, releasing high concentrations of NO, which exerts anti-tumor activity by inducing tumor cell apoptosis and inhibiting their repair. BNN6 can be used to synthesize the multifunctional biosensor BNN6-BiTiS3-iRGD, which exerts a synergistic anti-cancer effect with photothermal therapy (PTT) .

HY-P99144A

Anti-Mouse PD-1 Antibody (S-5001) 1 Publications Verification	PD-1/PD-L1	Inflammation/Immunology Cancer
Anti-Mouse PD-1 Antibody (S-5001) is a selective inhibitor targeting PD-1, blocking the PD-1/PD-L1 immune checkpoint axis through competitive binding to PD-1. Anti-Mouse PD-1 Antibody (S-5001) works by reversing the tumor immunosuppressive microenvironment and reactivating the anti-tumor activity of cytotoxic T lymphocytes. It can be used in research on tumors such as melanoma and HPV-positive oropharyngeal squamous cell carcinoma. Anti-Mouse PD-1 Antibody (S-5001) is often combined with photothermal therapy, chemotherapy, etc., to enhance efficacy .

HY-118924

IR-825	Fluorescent Dye	Cancer
IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal study. .

HY-W250126

Ethylene-vinyl acetate copolymer Poly(ethylene-co-vinyl acetate)	Environmental Pollutants Biochemical Assay Reagents	Others
Ethylene-vinyl acetate copolymer (Poly(ethylene-co-vinyl acetate)) is an encapsulant. Ethylene-vinyl acetate copolymer is cross-linked by a thermally activated reaction with peroxides. Ethylene-vinyl acetate copolymer can be used for encapsulation of photovoltaic modules .

HY-D1950

ATTO 633	Fluorescent Dye	Others
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .

HY-W248587

Cryptocyanine	Fluorescent Dye	Others
Cryptocyanine is a fluorescent dye .

HY-W441016

DSPE-PEG5000-NHS	Liposome	Others
DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .

HY-D1450

IR-1048 S01448	Fluorescent Dye	Cancer
IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .

HY-W879228

Disulfo-ICG-DBCO disodium	Fluorescent Dye	Others
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .

HY-157529

IR820-PTX	Microtubule/Tubulin Fluorescent Dye	Cancer
IR820-PTX, an IR-820 (HY-136886)-Paclitaxel (HY-B0015) conjugate, is an amphipathic small molecule prodrug. IR820-PTX effectively inhibits tumor growth via combined photothermal therapy (PTT) and chemotherapy .

HY-142533

HL-PEG2k	Biochemical Assay Reagents	Cancer
HL-PEG2k is a second near-infrared Ru(II) polypyridyl complex. HL-PEG2k exhibits a wavelength bathochromic shift, enhanced photothermal conversion efficiency (41.77%), and an antineoplastic effect against glioma. HL-PEG2k displays a superior biocompatibility and thus can be a potential theranostic platform to combat the growth and recurrence of tumors .

HY-139824

Nitro-coronene	Biochemical Assay Reagents	Cancer
Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal research of cancer.

HY-D2215

Mito-CCY	Fluorescent Dye	Cancer
Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .

HY-170490

TTQ-SA	Photosensitizer Apoptosis	Cancer
TTQ-SA is a near-infrared (NIR) spiro-AIEgen (aggregation-induced emission luminogen), that converts near-infrared light (NIR) into thermal energy, causing thermal damage and death of tumor cells. TTQ-SA exhibits cellular uptake and targeting ability in cancer cell MF-7. TTQ-SA silences the expression of survivin gene with combination of DNAzyme, enhances the sensitivity of tumor cells to photothermal therapy .

Cat. No.	Product Name	Type

HY-D1063

IR-780 5+ Cited Publications	Fluorescent Dyes
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .

IR-780

5+ Cited Publications

Fluorescent Dyes

IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .

HY-118924

IR-825	Fluorescent Dyes
IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal study. .

HY-D1950

ATTO 633	Fluorescent Dyes
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .

HY-W248587

Cryptocyanine	Fluorescent Dyes
Cryptocyanine is a fluorescent dye .

HY-W879228

Disulfo-ICG-DBCO disodium	Fluorescent Dyes
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .

HY-D2215

Mito-CCY	Fluorescent Dyes
Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .

Cat. No.	Product Name	Type

HY-W250126

Ethylene-vinyl acetate copolymer Poly(ethylene-co-vinyl acetate)	Biochemical Assay Reagents
Ethylene-vinyl acetate copolymer (Poly(ethylene-co-vinyl acetate)) is an encapsulant. Ethylene-vinyl acetate copolymer is cross-linked by a thermally activated reaction with peroxides. Ethylene-vinyl acetate copolymer can be used for encapsulation of photovoltaic modules .

Cat. No.	Product Name	Target	Research Area

HY-P11054

CREKA-YpFFK(Nph)	Peptides	Cancer
CREKA-YpFFK(Nph) is a gold nanoparticle surface ligand composed of CREKA and YPFFK (Nph), responsible for tumor targeting and alkaline phosphatase-responsive bond cleavage, respectively. CREKA-YpFFK(Nph) can be used for tumor targeting research .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99144A

Anti-Mouse PD-1 Antibody (S-5001) 1 Publications Verification	PD-1/PD-L1	Inflammation/Immunology Cancer
Anti-Mouse PD-1 Antibody (S-5001) is a selective inhibitor targeting PD-1, blocking the PD-1/PD-L1 immune checkpoint axis through competitive binding to PD-1. Anti-Mouse PD-1 Antibody (S-5001) works by reversing the tumor immunosuppressive microenvironment and reactivating the anti-tumor activity of cytotoxic T lymphocytes. It can be used in research on tumors such as melanoma and HPV-positive oropharyngeal squamous cell carcinoma. Anti-Mouse PD-1 Antibody (S-5001) is often combined with photothermal therapy, chemotherapy, etc., to enhance efficacy .

Cat. No.	Product Name		Classification

HY-W879228

Disulfo-ICG-DBCO disodium		DBCO
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .

Cat. No.	Product Name		Classification

HY-W441016

DSPE-PEG5000-NHS		Pegylated Lipids
DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Fluorescent Dyes

Biochemical Assay Reagents

Peptides

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Click Chemistry

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