1. GPCR/G Protein
  2. Vasopressin Receptor
  3. SKF 100398

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP.

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SKF 100398

SKF 100398 Estructura química

No. CAS : 77453-01-1

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500 μg En stock
1 mg En stock
5 mg En stock
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50 mg   Obtener un presupuesto  

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Descripciòn

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP[1].

In Vivo

SKF 100398 is a specific antagonist of the hydrosmotic effect of exogenous and endogenous AVP[1].
SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (250-300 g)[1]
Dosage: 8 μg/kg
Administration: Intravenous injection
Result: Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).
Peso molecular

1136.39

Fòrmula

C53H77N13O11S2

No. CAS
Appearance

Solid

Color

White to off-white

Sequence

{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-Cys6)

Sequence Shortening

{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-YFVNCPRG-NH2 (Disulfide bridge: 1-Cys6)

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación

Purity: 99.48%

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Inquiry Information

Nombre del producto:
SKF 100398
Cat. No.:
HY-P3066
Cantidad:
MCE Japan Authorized Agent: