2. Anti-infection
  3. Bacterial
  4. Sulfisoxazole acetyl

Sulfisoxazole acetyl  (Synonyms: N1-Acetylsulfisoxazole)

Art. -Nr.: HY-107923 Reinheit: 99.93%
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Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action.

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Sulfisoxazole acetyl

Sulfisoxazole acetyl Chemische Struktur

CAS. Nr. : 80-74-0

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
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Sulfisoxazole acetyl Related Antibodies

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Beschreibung

Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action[1].

In Vitro

As with other sulfonamides, the antibacterial action of Sulfisoxazole acetyl (N1-Acetylsulfisoxazole) is attributable to inhibiting dihydropteroate synthase, a key enzyme in folate synthesis in bacteria. Sulfisoxazole acetyl is known to be transformed primarily to sulfisoxazole, partly to N4-acetyl sulfisoxazole (N4AS), and likely also to diacetyl sulfisoxazole (DAS) and other compounds[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfisoxazole acetyl Related Antibodies
Molekulargewicht

309.34

Formel

C13H15N3O4S
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C)N(S(=O)(C1=CC=C(C=C1)N)=O)C2=C(C)C(C)=NO2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 250 mg/mL (808.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2327 mL 16.1634 mL 32.3269 mL
5 mM 0.6465 mL 3.2327 mL 6.4654 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2327 mL 16.1634 mL 32.3269 mL 80.8172 mL
5 mM 0.6465 mL 3.2327 mL 6.4654 mL 16.1634 mL
10 mM 0.3233 mL 1.6163 mL 3.2327 mL 8.0817 mL
15 mM 0.2155 mL 1.0776 mL 2.1551 mL 5.3878 mL
20 mM 0.1616 mL 0.8082 mL 1.6163 mL 4.0409 mL
25 mM 0.1293 mL 0.6465 mL 1.2931 mL 3.2327 mL
30 mM 0.1078 mL 0.5388 mL 1.0776 mL 2.6939 mL
40 mM 0.0808 mL 0.4041 mL 0.8082 mL 2.0204 mL
50 mM 0.0647 mL 0.3233 mL 0.6465 mL 1.6163 mL
60 mM 0.0539 mL 0.2694 mL 0.5388 mL 1.3470 mL
80 mM 0.0404 mL 0.2020 mL 0.4041 mL 1.0102 mL
100 mM 0.0323 mL 0.1616 mL 0.3233 mL 0.8082 mL
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Sulfisoxazole acetyl Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfisoxazole acetyl80-74-0N1-AcetylsulfisoxazoleBacterialSulfisoxazole derivativedihydropteroate synthaseantibacterial actionorally activeInhibitorinhibitorinhibit

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