Urotensin II-related peptide

Cat. No.: HY-P1165 Pureté: 99.52%: Fiche technique
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Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor.

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Synthèse de peptides personnalisée

Urotensin II-related peptide Chemical Structure

CAS No. : 342878-90-4

Size	Stock	Quantité
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtenir un devis
100 mg	Obtenir un devis

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Description

Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	12 1 Compound: 2, URP	Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis	[PMID: 24251366]
CHO	IC₅₀	12 1 Compound: 2, URP	Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis	[PMID: 24251366]

Masse moléculaire

1017.22

Formule

C₄₉H₆₄N₁₀O₁₀S₂

CAS No.

342878-90-4

Appearance

Solid

Color

White to off-white

Sequence

Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge:Cys2-Cys7)

Sequence Shortening

ACFWKYCV (Disulfide bridge:Cys2-Cys7)

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvant et solubilité

In Vitro:

DMSO : 100 mg/mL (98.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9831 mL	4.9154 mL	9.8307 mL
5 mM	0.1966 mL	0.9831 mL	1.9661 mL
10 mM	0.0983 mL	0.4915 mL	0.9831 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Pureté et documentation

Purity: 99.52%

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Fiche technique (279 KB) SDS (252 KB)

COA (260 KB) LCMS (93 KB) Elemental Analysis Report (118 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Lescot E, et al. Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships Peptides. 2008 May;29(5):680-90. [Content Brief]

[2]. Labarrère P, et al. Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction. J Enzyme Inhib Med Chem. 2003 Apr;18(2):77-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9831 mL	4.9154 mL	9.8307 mL	24.5768 mL
	5 mM	0.1966 mL	0.9831 mL	1.9661 mL	4.9154 mL
	10 mM	0.0983 mL	0.4915 mL	0.9831 mL	2.4577 mL
	15 mM	0.0655 mL	0.3277 mL	0.6554 mL	1.6385 mL
	20 mM	0.0492 mL	0.2458 mL	0.4915 mL	1.2288 mL
	25 mM	0.0393 mL	0.1966 mL	0.3932 mL	0.9831 mL
	30 mM	0.0328 mL	0.1638 mL	0.3277 mL	0.8192 mL
	40 mM	0.0246 mL	0.1229 mL	0.2458 mL	0.6144 mL
	50 mM	0.0197 mL	0.0983 mL	0.1966 mL	0.4915 mL
	60 mM	0.0164 mL	0.0819 mL	0.1638 mL	0.4096 mL
	80 mM	0.0123 mL	0.0614 mL	0.1229 mL	0.3072 mL