1. Anti-infection
  2. HBV
  3. Xalnesiran

Xalnesiran (RO7445482) is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran can be used for the research of chronic hepatitis B infection.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

RNA, (Gm-sp-Am-(2′-deoxy-2′-fluoro)C-Am-Am-Am-Am-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-Cm-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-Am-Cm-Am-(2′-deoxy-2′-fluoro)A-Um-Am-Am-Gm-Cm-Am-Gm-Cm-Cm-[2′-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]G-[2′-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2′-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2′-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm), complex with RNA ([4′-de(hydroxymethyl)-4′-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2′-deoxy-2′-fluoro)U-sp-(2′-deoxy-2′-fluoro)A-sp-Um-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)G-Am-(2′-deoxy-2′-fluoro)G-Gm-(2′-deoxy-2′-fluoro)A-Um-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)U-Um-Gm-(2′

Xalnesiran Chemische Struktur

CAS. Nr. : 2538784-48-2

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Beschreibung

Xalnesiran (RO7445482) is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran can be used for the research of chronic hepatitis B infection[1][2][3].

In Vitro

Xalnesiran silences multiple HBV transcripts via post-transcriptional gene silencing, and suppresses hepatitis B surface antigen production[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

21009.15

Formel

C664H871F17N231O415P57S6

CAS. Nr.
SMILES

[Xalnesiran]

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation
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  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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