Xalnesiran sodium
Based on 1 Customer Validation
Xalnesiran (RO7445482) sodium is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran sodium can be used for the research of chronic hepatitis B infection.
For research use only. We do not sell to patients.
- Purity: 95.90%
- CAS No.: 2538784-49-3
- Formula: C664H814F17N231Na57O415P57S6
- Molecular Weight:21009.2 (free acid)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 2538784-49-3
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Appearance Solid
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Molecular Weight 21009.2 (free acid)
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Formula C664H814F17N231Na57O415P57S6
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Color White to off-white
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SMILES
[Xalnesiran (sodium)]
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Synonyms
RO7445482 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2242 KB)
References
[1]. Hui RW, et al. Emerging therapies for HBsAg seroclearance: spotlight on novel combination strategies. Hepatol Int. 2025;19(4):704-719. [Content Brief]
[2]. Tang Q, et al. Xalnesiran with or without an immunomodulator in chronic hepatitis B: still a challenge in functional cure. Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):348-350. [Content Brief]
[3]. Hou J, et al. Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B. N Engl J Med. 2024 Dec 5;391(22):2098-2109. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)