2538784-49-3
Chemical Structure
Xalnesiran sodium
Synonym(s): RO7445482 sodium
- CAS No.: 2538784-49-3
- Formula:C664H814F17N231Na57O415P57S6
- Molecular Weight:21009.2 (free acid)
SMILES: [Xalnesiran (sodium)]
Biological Activity:
Xalnesiran (RO7445482) sodium is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran sodium can be used for the research of chronic hepatitis B infection[1][2][3].
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Xalnesiran sodium | 95.90% | Xalnesiran (RO7445482) sodium is a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome. Xalnesiran sodium can be used for the research of chronic hepatitis B infection. |
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- [1]. Hui RW, et al. Emerging therapies for HBsAg seroclearance: spotlight on novel combination strategies. Hepatol Int. 2025;19(4):704-719. [Content Brief]
- [2]. Tang Q, et al. Xalnesiran with or without an immunomodulator in chronic hepatitis B: still a challenge in functional cure. Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):348-350. [Content Brief]
- [3]. Hou J, et al. Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B. N Engl J Med. 2024 Dec 5;391(22):2098-2109. [Content Brief]
Keywords