2538784-48-2
2538784-48-2
Chemical Structure
Xalnesiran
Synonym(s): RO7445482
- CAS. Nr.: 2538784-48-2
- Formula:C664H871F17N231O415P57S6
- Molecular Weight:21009.15
IUPAC Name: sodium (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-((methoxy-d3)imino)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES: [Xalnesiran]
Biological Activity:
Xalnesiran (RO7445482) is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran can be used for the research of chronic hepatitis B infection[1][2][3].
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Xalnesiran | Xalnesiran (RO7445482) is a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome. Xalnesiran can be used for the research of chronic hepatitis B infection. |
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References
- [1]. Hui RW, et al. Emerging therapies for HBsAg seroclearance: spotlight on novel combination strategies. Hepatol Int. 2025;19(4):704-719. [Content Brief]
- [2]. Tang Q, et al. Xalnesiran with or without an immunomodulator in chronic hepatitis B: still a challenge in functional cure. Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):348-350. [Content Brief]
- [3]. Hou J, et al. Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B. N Engl J Med. 2024 Dec 5;391(22):2098-2109. [Content Brief]
Keywords
