1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d₇₀  (Synonyms: DSPE-d₇₀)

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d₇₀ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

818.50

C₄₁H₁₂D₇₀NO₈P

326495-43-6

1069-79-0

Solid

White to off-white

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Room temperature in continental US; may vary elsewhere.

• [1]. McCarley RL, et al. Redox-responsive delivery systems. Annu Rev Anal Chem (Palo Alto Calif). 2012;5:391-411.  [Content Brief]

  [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.  [Content Brief]