2. Anti-infection
  3. HIV Reverse Transcriptase
  4. 1,6-Di-O-galloyl-β-D-glucose

1,6-Di-O-galloyl-β-D-glucose 

製品番号: HY-W719041 純度: 91.11%
COA 取扱説明書 Technical Support

1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP). 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research.

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1,6-Di-O-galloyl-β-D-glucose

1,6-Di-O-galloyl-β-D-glucose 構造式

CAS 番号 : 23363-08-8

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1 mg $430 在庫あり
5 mg $1075 在庫あり
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1,6-Di-O-galloyl-β-D-glucose 関連抗体

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製品説明

1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP). 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research[1].

Cellular Effect
Cell Line Type Value Description References
A549 ED50
> 10 μg/mL
Compound: 5
Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay
Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay
[PMID: 1431932]
HCT-8 ED50
> 10 μg/mL
Compound: 5
Cytotoxicity against human HCT8 cells by tetrazolium salt-based colorimetric assay
Cytotoxicity against human HCT8 cells by tetrazolium salt-based colorimetric assay
[PMID: 1431932]
KB ED50
> 10 μg/mL
Compound: 5
Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay
Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay
[PMID: 1431932]
TE-671 ED50
> 10 μg/mL
Compound: 5
Cytotoxicity against human TE671 cells by tetrazolium salt-based colorimetric assay
Cytotoxicity against human TE671 cells by tetrazolium salt-based colorimetric assay
[PMID: 1431932]
分子量

484.36

分子式

C20H20O14
CAS 番号
Appearance

Solid

Color

Brown to black

SMILES

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)COC(C3=CC(O)=C(C(O)=C3)O)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
純度とドキュメンテーション

純度: 91.11%

COA (250 KB)

取扱説明書 (2659 KB)
参考文献
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1,6-Di-O-galloyl-β-D-glucose Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,6-Di-O-galloyl-β-D-glucose23363-08-8HIVReverse TranscriptaseHuman immunodeficiency virusRTInhibitorinhibitorinhibit

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製品名:
1,6-Di-O-galloyl-β-D-glucose
製品番号:
HY-W719041
数量:
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