2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 14,15-Epoxyeicosatrienoic acid

14,15-Epoxyeicosatrienoic acid  (Synonyms: 14,15-EET)

製品番号: HY-113489
COA 取扱説明書 Technical Support

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research.

It is advisable to consider the similar product ((±)14,15-Epoxyeicosatrienoic acid) that retains the same biological activity.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

14,15-Epoxyeicosatrienoic acid

14,15-Epoxyeicosatrienoic acid 構造式

CAS 番号 : 81276-03-1

容量 価格（税別） 在庫状況
Solvent
25 μg (312.04 μM * 250 μL in Ethanol) USD 350 見積もりとリードタイムを求めるのご確認
Solvent
50 μg (312.04 μM * 500 μL in Ethanol) USD 560 見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

14,15-Epoxyeicosatrienoic acid 関連抗体

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製品説明

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外実験

14,15-Epoxyeicosatrienoic acid (0-10 μM) promotes Aβ uptake in primary astrocyte cultures[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

14,15-Epoxyeicosatrienoic acid 関連抗体
体内実験

14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in mouse cerebral arterioles[2].
14,15-Epoxyeicosatrienoic acid (200 ng/ml) infusion into the hippocampus reversed Aβ deposition in the brains of 6-month-old male FAD mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

320.47

分子式

C20H32O3
CAS 番号
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(O)CCC/C=C/C/C=C/C/C=C/CC1OC1CCCCC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Solution, -20°C, 2 years
純度とドキュメンテーション

純度: 99.9%

COA (239 KB)

取扱説明書 (2659 KB)
参考文献
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14,15-Epoxyeicosatrienoic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

14,15-Epoxyeicosatrienoic acid81276-03-114,15-EETEndogenous MetaboliteAlzheimer's diseaseastrocytelysosomal biogenesissoluble epoxide hydrolaseInhibitorinhibitorinhibit

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製品名:
14,15-Epoxyeicosatrienoic acid
製品番号:
HY-113489
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