2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2’-Deoxy-2’-fluoroinosine

2’-Deoxy-2’-fluoroinosine  (Synonyms: 2'-Fluoro-2'-deoxyinosine)

Cat. No.: HY-482934
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2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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2’-Deoxy-2’-fluoroinosine

2’-Deoxy-2’-fluoroinosine Chemical Structure

CAS No. : 80049-87-2

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2’-Deoxy-2’-fluoroinosine Related Antibodies

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Description

2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
CCRF-CEM IC50
>100 μM
Compound: 15
The cytotoxicity against CEM cells
The cytotoxicity against CEM cells
[PMID: 9276020]
HepG2 EC50
8 μM
Compound: 15
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
[PMID: 9276020]
HepG2 IC50
>200 μM
Compound: 15
The cytotoxicity against 2.2.15 cells expressed as IC50
The cytotoxicity against 2.2.15 cells expressed as IC50
[PMID: 9276020]
Masse moléculaire

270.22

Formule

C10H11FN4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

F[C@H]1[C@@H](O[C@@H]([C@H]1O)CO)N2C3=C(C(N=CN3)=O)N=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Pureté et documentation
Références
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2’-Deoxy-2’-fluoroinosine Related Classifications

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2’-Deoxy-2’-fluoroinosine80049-87-22'-Fluoro-2'-deoxyinosineNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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