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  4. 3-Indoleacetic acid

インドール-3-酢酸  (Synonyms: 3-Indoleacetic acid; 3-インドール酢酸3-IAA)

製品番号: HY-18569 純度: 99.94%
COA 取扱説明書 Technical Support

3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 87-51-4

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 55 在庫あり
Solution
10 mM * 1 mL in DMSO USD 55 在庫あり
Solid
500 mg $50 在庫あり
5 g $60 在庫あり
10 g $72 在庫あり
25 g $110 在庫あり
50 g $160 在庫あり
100 g $224 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 21 publication(s) in Google Scholar

Other Forms of 3-Indoleacetic acid:

インドール-3-酢酸 関連抗体

Top Publications Citing Use of Products

    3-Indoleacetic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 25:e04688.  [Abstract]

    3-IAA (50, 100 mg/kg; once daily; 18 days) significantly inhibited tumor growth in a dose-dependent manner.

    3-Indoleacetic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 25:e04688.  [Abstract]

    3-IAA (50, 100 mg/kg; once daily; 6 weeks) significantly reduced bioluminescent signal in the footpads and popliteal lymph nodes; the higher the concentration, the more significant the reduction.

    3-Indoleacetic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 25:e04688.  [Abstract]

    The proliferation of T24 and 5637 cells after treatment with different concentrations of 3-IAA for 24 or 48 hours was evaluated using the CCK-8 assay.

    3-Indoleacetic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 25:e04688.  [Abstract]

    Representative images of T24 and 5637 cells were observed after treatment with different concentrations of 3-IAA (300 µM and 600 µM; 24 h) or DMSO.

    3-Indoleacetic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 25:e04688.  [Abstract]

    Representative images of wound healing assays were observed after treating T24 and 5637 cells with different concentrations of 3-IAA (300 µM and 600 µM; 24 h) or DMSO.

    Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Human Endogenous Metabolite Microbial Metabolite

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis[2].
    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    体外実験

    3-Indoleacetic acid promotes the enrichment of salt tolerant bacteria with growth promoting function during the secondary fermentation process of compost[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    インドール-3-酢酸 関連抗体
    体内実験

    3-Indoleacetic acid (50 g/ha) improves outcrossing rate of diverse rice cytoplasmic male sterile lines and hybrid rice seed production through affecting floral traits[2].
    3-Indoleacetic acid (10 mg/kg) improves photosynthetic performance and reduces the toxic effect of cadmium on C. camphora[3].
    3-Indoleacetic acid (500 mg/kg, once daily, 14 days, p.o.) exhibits adverse effects on liver and kidney function, myocardial and skeletal muscles, and testes in rats[4].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: adult male Wistar albino rat[4].
    Dosage: 500 mg/kg body weight, once daily, 14 days
    Administration: oral gavage (p.o.)
    Result: Reduced the number of red blood cells and white blood cells[4].
    分子量

    175.19

    分子式

    C10H9NO2
    CAS 番号
    Appearance

    Solid

    Color

    Off-white to light brown

    SMILES

    OC(CC1=CNC2=C1C=CC=C2)=O
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    溶剤 & 溶解度
    体外: 

    DMSO : 125 mg/mL (713.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    H2O : 1 mg/mL (5.71 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 5.7081 mL 28.5404 mL 57.0809 mL
    5 mM 1.1416 mL 5.7081 mL 11.4162 mL
    10 mM 0.5708 mL 2.8540 mL 5.7081 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2.08 mg/mL (11.87 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.08 mg/mL (11.87 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  Corn Oil

      Solubility: 6.67 mg/mL (38.07 mM); Suspended solution; Need ultrasonic

    • Protocol 2

      Add each solvent one by one:  50% PEG300    50% Saline

      Solubility: 50 mg/mL (285.40 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    % 
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    純度とドキュメンテーション

    純度: 99.94%

    COA (252 KB) LCMS (94 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO 1 mM 5.7081 mL 28.5404 mL 57.0809 mL 142.7022 mL
    5 mM 1.1416 mL 5.7081 mL 11.4162 mL 28.5404 mL
    DMSO 10 mM 0.5708 mL 2.8540 mL 5.7081 mL 14.2702 mL
    15 mM 0.3805 mL 1.9027 mL 3.8054 mL 9.5135 mL
    20 mM 0.2854 mL 1.4270 mL 2.8540 mL 7.1351 mL
    25 mM 0.2283 mL 1.1416 mL 2.2832 mL 5.7081 mL
    30 mM 0.1903 mL 0.9513 mL 1.9027 mL 4.7567 mL
    40 mM 0.1427 mL 0.7135 mL 1.4270 mL 3.5676 mL
    50 mM 0.1142 mL 0.5708 mL 1.1416 mL 2.8540 mL
    60 mM 0.0951 mL 0.4757 mL 0.9513 mL 2.3784 mL
    80 mM 0.0714 mL 0.3568 mL 0.7135 mL 1.7838 mL
    100 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.4270 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    3-Indoleacetic acid Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    3-Indoleacetic acid87-51-4Indole-3-acetic acid 3-IAAEnvironmental PollutantsEndogenous MetaboliteEnvironmental Contaminantsnatural plant hormonesplant growth regulatorphotosynthesisInhibitorinhibitorinhibit

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    製品名:
    3-Indoleacetic acid
    製品番号:
    HY-18569
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