1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 4-Amino-3-hydroxyphenylalanine

4-Amino-3-hydroxyphenylalanine dihydrochloride (4-AHP) is a photodegradation product of eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used to investigate the development of cutaneous melanoma and age-related macular degeneration.

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4-Amino-3-hydroxyphenylalanine

4-Amino-3-hydroxyphenylalanine Estructura química

No. CAS : 74923-08-3

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Descripciòn

4-Amino-3-hydroxyphenylalanine dihydrochloride (4-AHP) is a photodegradation product of eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used to investigate the development of cutaneous melanoma and age-related macular degeneration[1].

In Vitro

4-Amino-3-hydroxyphenylalanine (1-7 days) levels decrease time-dependently upon UVA irradiation of human red hair pheomelanin, reflecting the conversion of photolabile benzothiazine moieties to benzothiazole moieties[1].
4-Amino-3-hydroxyphenylalanine (70-157 h) levels decrease time-dependently upon blue light irradiation of bovine RPE melanosomes, reflecting photooxidative conversion of benzothiazine moieties to benzothiazole moieties in pheomelanin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

196.20

Fòrmula

C9H12N2O3

No. CAS
SMILES

OC([C@@H](N)CC1=CC(O)=C(C=C1)N)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Inquiry Information

Nombre del producto:
4-Amino-3-hydroxyphenylalanine
Cat. No.:
HY-W997836
Cantidad:
MCE Japan Authorized Agent: