1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 4-Amino-3-hydroxyphenylalanine dihydrochloride

4-Amino-3-hydroxyphenylalanine dihydrochloride  (Synonyms: 4-AHP dihydrochloride)

Cat. No.: HY-W997836A Purity: 98.97%
Handling Instructions Technical Support

4-Amino-3-hydroxyphenylalanine dihydrochloride is a photodegradation product of Eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used for research of melanomagenesis in the skin and age-related macular degeneration.

For research use only. We do not sell to patients.

4-Amino-3-hydroxyphenylalanine dihydrochloride

4-Amino-3-hydroxyphenylalanine dihydrochloride Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

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Other Forms of 4-Amino-3-hydroxyphenylalanine dihydrochloride:

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Description

4-Amino-3-hydroxyphenylalanine dihydrochloride is a photodegradation product of Eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used for research of melanomagenesis in the skin and age-related macular degeneration[1].

Molecular Weight

269.13

Formula

C9H14Cl2N2O3

Appearance

Solid

Color

Light brown to brown

SMILES

OC([C@@H](N)CC1=CC(O)=C(C=C1)N)=O.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, protect from light

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (37.16 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7157 mL 18.5784 mL 37.1568 mL
5 mM 0.7431 mL 3.7157 mL 7.4314 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.7157 mL 18.5784 mL 37.1568 mL 92.8919 mL
5 mM 0.7431 mL 3.7157 mL 7.4314 mL 18.5784 mL
10 mM 0.3716 mL 1.8578 mL 3.7157 mL 9.2892 mL
15 mM 0.2477 mL 1.2386 mL 2.4771 mL 6.1928 mL
20 mM 0.1858 mL 0.9289 mL 1.8578 mL 4.6446 mL
25 mM 0.1486 mL 0.7431 mL 1.4863 mL 3.7157 mL
30 mM 0.1239 mL 0.6193 mL 1.2386 mL 3.0964 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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4-Amino-3-hydroxyphenylalanine dihydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4-Amino-3-hydroxyphenylalanine dihydrochloride
Cat. No.:
HY-W997836A
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