5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin 

5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin is a porphyrin compound. 5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin exhibits virucidal effects of 85% and 60% against HSV-1 and HSV-2, respectively. 5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin has a maximum noncytotoxic studied concentration of 5 μg/mL on Vero cells. 5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin can be used for the synthesis of compounds with stronger antiviral activity^[1].

658.75

C₄₅H₃₀N₄O₂

95051-10-8

Solid

Dark purple to black

O=C(C1=CC=C(/C2=C3C=CC(/C(C4=CC=CC=C4)=C5C=C/C(N/5)=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C2N9)=N\3)C=C1)O

Room temperature in continental US; may vary elsewhere.

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Tomé JP, et al. Synthesis of glycoporphyrin derivatives and their antiviral activity against herpes simplex virus types 1 and 2. Bioorg Med Chem. 2005 Jun 2;13(12):3878-88.  [Content Brief]