5,7-Dichlorokynurenic acid sodium (Synonyms: 5,7-DCKA sodium)

Cat. No.: HY-100834A: FAQs
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5,7-Dichlorokynurenic acid (sodium) is the sodium form of 5,7-Dichlorokynurenic acid (HY-100834). 5,7-Dichlorokynurenic acid is a selective and competitive antagonist of the glycine site on the NMDA receptor with a K_B of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduces NMDA-induced neuron injury in rat cortical cell cultures.

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5,7-Dichlorokynurenic acid sodium Chemical Structure

CAS No. : 1184986-70-6

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5,7-Dichlorokynurenic acid

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Description	5,7-Dichlorokynurenic acid (sodium) is the sodium form of 5,7-Dichlorokynurenic acid (HY-100834). 5,7-Dichlorokynurenic acid is a selective and competitive antagonist of the glycine site on the NMDA receptor with a K_B of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduces NMDA-induced neuron injury in rat cortical cell cultures^[1].
Molecular Weight	280.04
Formula	C₁₀H₄Cl₂NNaO₃
CAS No.	1184986-70-6
SMILES	O=C(C1=NC2=CC(Cl)=CC(Cl)=C2C(O)=C1)O[Na]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. D McNamara, et al. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett. 1990 Nov 27;120(1):17-20. [Content Brief] [2]. McNamara D, et al. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett. 1990 Nov 27;120(1):17-20. [Content Brief]

5,7-Dichlorokynurenic acid sodium Related Classifications

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Do most proteins show cross-species activity?
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Keywords:

5,7-Dichlorokynurenic acid1184986-70-65,7-DCKAiGluRIonotropic glutamate receptorssodiumNMDAkynurenic acidderivativeneuron injuryInhibitorinhibitorinhibit

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5,7-Dichlorokynurenic acid sodium (Synonyms: 5,7-DCKA sodium)

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