5-Aza-7-deazaguanine

Name: 5-Aza-7-deazaguanine
Brand: MedChemExpress
SKU: HY-111627
Rating: 4.5 (1 reviews)

製品番号: HY-111627 純度: 99.86%: Data Sheet SDS COA 取扱説明書
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5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

5-Aza-7-deazaguanine 構造式

CAS 番号 : 67410-64-4

容量	価格（税別）	在庫状況	数量
5 mg	$130	在庫あり	Estimated Time of Arrival: December 31
10 mg	$220	在庫あり	Estimated Time of Arrival: December 31
25 mg	$450	在庫あり	Estimated Time of Arrival: December 31
50 mg	$740	在庫あり	Estimated Time of Arrival: December 31
100 mg	$1180	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

顧客検証

•Theranostics. 2021 Jan 1;11(2):841-860. [Abstract]

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•関連スクリーニングライブラリ:

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•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides^[1].

IC₅₀ & Target

Purine nucleoside phosphorylase, Nucleoside Antimetabolite/Analog^[1]

分子量

151.13

分子式

C₅H₅N₅O

CAS 番号

67410-64-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N=C(N)N=C2N1C=CN2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

H₂O : 5 mg/mL (33.08 mM; ultrasonic and adjust pH to 9 with NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6168 mL	33.0841 mL	66.1682 mL
5 mM	1.3234 mL	6.6168 mL	13.2336 mL
10 mM	0.6617 mL	3.3084 mL	6.6168 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.86%

Select Batch:

データシート (272 KB) SDS (252 KB)

COA (249 KB) RP-HPLC (254 KB) MS (68 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Fateev IV, et al. Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides. Chemistry. 2015 Sep 14;21(38):13401-19. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.6168 mL	33.0841 mL	66.1682 mL	165.4205 mL
	5 mM	1.3234 mL	6.6168 mL	13.2336 mL	33.0841 mL
	10 mM	0.6617 mL	3.3084 mL	6.6168 mL	16.5420 mL
	15 mM	0.4411 mL	2.2056 mL	4.4112 mL	11.0280 mL
	20 mM	0.3308 mL	1.6542 mL	3.3084 mL	8.2710 mL
	25 mM	0.2647 mL	1.3234 mL	2.6467 mL	6.6168 mL
	30 mM	0.2206 mL	1.1028 mL	2.2056 mL	5.5140 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.